摘要
目的通过调查我院儿科住院患者医嘱的超说明书用药情况,分析儿科患者用药存在的问题,从而规避用药风险。方法随机抽取我院儿科2017年1—12月出院患儿院内用药医嘱,判断及统计其是否超说明书用药并进行分析。结果 297份病例共计医嘱总数4 537条,超说明书医嘱数1 692条(37.29%)。超说明书用药前3位类型为超给药剂量(41.96%)、超适应年龄(20.80%)和未提及儿童用药信息(20.22%)。超说明书用药医嘱发生率前3位的年龄段为婴幼儿(53.07%)、学龄前(42.56%)和学龄期(38.35%),发生率较高的前3位的3类药物分别为平喘药(79.90%)、皮质激素类药物(47.85%)和维生素类药物(43.08%)。超说明书用药医嘱合理率为90.72%。结论我院儿科住院患者超说明书用药情况较为普遍,但属于不合理用药的比例较低,用药基本合理。
Objective To determine the extent of off-label drug use in pediatric wards of our hospital in 2017.MethodsTwo hundred ninety-seven patient records of pediatrics were randomly selected in 2017.According to drugs＇instructions,the data of off-label prescriptions was analyzed.Results We found 1 692 off-label prescriptions in total 4 537 prescriptions which were amounted to 37.29%.The top three types with off-label drug use were over dosage（41.96%）,over indications（20.80%）and no pediatric information（20.22%）.The top three groups of patients with highest incidence rate of off-label drug use were infants（53.07%）,before school-age（42.56%）,school-age（38.35%）.The top three drugs with highest incidence rate of off-label drug use were antiasthmastic drugs（79.90%）,corticosteroids（47.85%）and vitamins（43.08%）.However,the proportion of reasonable prescriptions was 90.72%.Conclusion The off-label drug use in our hospital is common,but the proportion of unreasonable prescriptions is low.
作者
杨李娜
黄献川
陈宜锋
YANG Lina;HUANG Xianchuan;CHEN Yifeng(Department of Pharmacy, the Affiliated Zhangzhou Municipal Hospital, Fujian Medical University Zhangzhou, Fujian 363000, Chin)
出处
《福建医药杂志》
CAS
2018年第2期118-120,共3页
Fujian Medical Journal
关键词
超说明书用药
儿科
用药安全
pediatrics
off label drug use
drug safety
