摘要
目的了解本院药品不良反应发生的特点,促进合理用药。方法对解放军第三一六医院2009年1月～2012年11月收集到的302例药品不良反应(ADR)报告进行回顾性分析。结果 >65岁人群发生ADR的比例最高,有108例(35.76%);静脉滴注引起的ADR有240例(79.47%);ADR主要累及的器官为皮肤及其附件,有154例(50.99%);严重ADR26例,其中以发生过敏性休克为主,有9例;引起ADR的药品有15类63种,抗菌药物居首位,有147例(48.68%),抗菌药中以喹诺酮类药物居首位,有66例(44.90%)。结论加强药学监护与ADR监测一体模式的实践,加强ADR信息的宣传教育,减少和避免ADR的发生,促进安全用药。
Objective To probe into the characteristics of ADRs in PLA 316 hospita! and promote the rational use of drugs. Methods ADR cases collected from a PLA 316 hospital between December 2008 and November 2012 were retrospectively analyzed. Results The incidence of ADR cases was the highest in patients above 65 years old（n=108,35.76%）.240 ADR cases were induced by intravenous administration （79.g7%）.Main clinical manifestation in 154 cases were lesion of skin and its appendices （50.99%）.The incidence of allergic shock was the highest（n=9） of the 26 severe ADR cases,15 categories（63 kinds） of drugs led to ADRs, in which the incidence of ADRs caused by antibiotic was the highest （n=147,48.68%）. Of the antibiotics, the incidence of quinolones was the highest （n=66, 44.90%）. Conclusion Attention should be attached to the education of rational drug use and the ADR monitoring to reduce and avoid the incidence of ADRs.
出处
《中国医药科学》
2013年第7期164-166,175,共4页
China Medicine And Pharmacy
关键词
药品不良反应
监测
合理用药
Adverse drug reaction
Monitoring
Rational drug use
