摘要
利用TracePro软件设计微流控液滴检测光学系统,构建系统组件模型,对不同尺寸和形状的液滴与气泡通过检测窗口所引起的光强信号变化进行仿真,分析光强信号与液滴尺寸和形状之间的关系。同时,搭建光学检测实验平台,对微流控芯片中生成的液滴和气泡进行实验测试,实验结果与仿真结果吻合。结果表明,液滴直径越大,光强越大,液滴纵向长度越长,波峰间距就越宽,同时能够区分气泡和液滴。通过TracePro软件仿真可以优化光学系统设计,为搭建光学实验平台提供参考。该光学检测系统可以用于监控液滴尺寸的均一性、计算液滴的生成频率和精准统计液滴的数量。
The optical detection system of the microfluidic droplet was designed by the TracePro software,and the component models of the system were built.The change of the optical intensity signal was simulated,which was caused by the droplets with different sizes and bubbles with different shapes flowing through the detection window.Then,the relationships between the optical intensity signal and the sizes,shapes of the droplets were analyzed.Meanwhile,an optical detection experiment apparatus was built to detect the droplets and bubbles formed in the microfluidic chips.The experimental results are accordant with the simulation results.The results show that the greater the diameter of the droplet is,the greater the optical intensity is;the longer the longitudinal length of the droplet is,the wider the peak separation is;meanwhile the droplet and bubble can be distinguished.The design of the optical system was optimized by the simulation of TracePro software to provide a reference for building the optical experiment platform.The optical detection system can be used to monitor the size uniformity of droplets,calculate the formation frequency of droplets and count the number of droplets accurately.
作者
张道森
王姗姗
何冠楠
关烨锋
Zhang Daosen;Wang Shanshan;He Guannan;Guan Yefeng(Guangdong Shunde Industrial Design Institute （Guangdong Shunde Innovative Design Institute）, Foshan 528311, China;School of Electromechanical Engineering, Guangdong University of Technology, Guangzhou 510006, China)
出处
《微纳电子技术》
北大核心
2018年第5期371-379,共9页
Micronanoelectronic Technology
