摘要
丹参是一种传统的中药,在临床治疗上发挥着积极作用。近年来,对丹参的化学成分、成分转化及其药代动力学等方面的研究均取得了较大进展。但中药含多种成分,各成分间存在着拮抗、协同或转化等作用,有关丹参有效成分间的相互转化和药代动力学方面缺乏相关总结综述。文章就近年来丹参有效成分间的相互转化及药代动力学研究进行综述,为丹参的开发提供参考价值。
Salvia miltiorrhiza is a kind of traditional Chinese medicine,playing an active role in the clinical treatment. Recently,great progress has been made in the studies on the chemical constituents,chemical composition transformation and pharmacokinetics of Salvia miltiorrhiza. But traditional Chinese medicine is a complex hybrid system. There are antagonistic,synergistic or transforming effects among the components and there is no summary about the mutual transformation and pharmacokinetics of effective components in Salvia miltiorrhiza. This article reviews the research progress of chemical composition transformation and pharmacokinetics of Radix Salvia miltiorrhiza in recent years and provides valuable reference for its research and development.
作者
栾茹乔
李慧芬
张学兰
徐保鑫
刁家葳
LUAN Ruqiao;LI Huifen;ZHANG Xuelan;XU Baoxin;DIAO Jiawei(Shandong University of TCM, Jinan 250355, Shandong, China;TCM Processing Technology Inherit Base, State Administration of TCM ,Jinan 250355, Shandong, China)
出处
《辽宁中医杂志》
CAS
2018年第2期437-439,共3页
Liaoning Journal of Traditional Chinese Medicine
基金
国家自然科学基金面上项目(81503251)
国家公共卫生专项(国中医药科技[2015]86号)
国家中药标准化项目(ZYBZH-Y-SH-38)
山东省高等学校科技计划项目(J15LM05)
山东省中医药科技发展计划项目(2015-020)
关键词
丹参
化学成分转化
药代动力学
研究进展
Salvia miltiorrhiza
chemical composition transformation
pharmacokinetics
research progress
