摘要
目的 探讨光学表面成像（OSI）系统（Catalyst）用于引导放疗摆位的精度和稳定性。方法 选取行全程CBCT引导放疗的5种不同肿瘤部位共52例肿瘤患者。首次治疗患者摆位后行CBCT配准修正并记录摆位误差为C,Catalyst拍下此时患者表面图像信息为参考图像Cref。非首次治疗患者按Catalyst Cref参考图像初步摆位（±2 mm/2°）,记录此时与Cref摆位误差为C1,再进行CBCT配准修正并记录摆位误差为C,修正后的表面图像与Cref误差为C2。记同次Catalyst摆位误差值C1与CBCT摆位误差C差值为d1,CBCT修正后Catalyst与参考图像误差C2为d2,两次误差值之差为d3（d3=d1-d2）。d1和d3的6D方向数值均采用t检验,Pearson法分析C与C1和d1与d2之间相关性。结果 52例患者d1和d3均值均在2 mm/2°以内,CBCT与C1和d1与d2值均呈显著相关（R=3、7,P=0.00、0.01）。结论 OSI系统用于引导放疗摆位有较高精度和稳定性,对于肿瘤放疗摆位有一定指导意义。
Objective To investigate the precision and stability of optical surface imaging （OSI） system Catalyst in guiding radiotherapy positioning. Methods A total of 52 patients with five different tumor sites who underwent cone-beam computed tomography （CBCT）-guided radiotherapy were recruited in this investigation. For the first treatment fraction,the setup error was recorded as C after online CBCT correction, and the surface images of patients taken by Catalyst were set as the reference images Cref. For the following treatment fraction,patients were pre-corrected according to the Catalyst Cref image with the acceptable errors within 2 mm/ 2,and the pre-corrected errors were recorded as C1.Then,after online CBCT correction,the setup errors were recorded as C.The errors between post-corrected Catalyst surface image and Cref image were recorded as C2.For each treatment fraction,the difference between Catalyst correction errors C1 and CBCT corrected errors C was recorded as d1, and the difference between the post-corrected Catalyst errors C2 and Cref image was recorded as d2. d3=d1-d2.The values of d1 and d3 in the 6 dimensions were analyzed using single sample t-test. The correlation between C-C1 and d1-d2 was statistically analyzed by Pearson correlation analysis. Results The mean value of d1 and d3 for 52 patients were within 2 mm/ 2 °. CBCT-C1 and d1-d2 were both significantly correlated （R=3,7,P=0.00,0.01）. Conclusions OSI system yield high accuracy and stability in radiotherapy positioning,which is of certain significance in radiotherapy positioning for cancer patients.
作者
杨露
钟仁明
李光俊
沈九零
李丽琴
柏森
Department of Radiotherapy, Renmin Hospital of Wuhan University, Wuhan 430060, China(Yang L ） ; Radiation Physics Technology Center, West China Hospital of Sichuan University, Chengdu 610041 ,Chi)
出处
《中华放射肿瘤学杂志》
CSCD
北大核心
2018年第4期387-391,共5页
Chinese Journal of Radiation Oncology
基金
四川省科技厅项目（2016JY0072）
