摘要
目的:探讨CT/CT图像融合技术在非小细胞肺癌放射治疗缩野时计划评估中的应用。方法:选择2006年6月-2006年12月11例实施三维适形放射治疗的非小细胞肺癌(NSCLC)患者,在放疗前和疗程中缩野时分别行CT扫描,每个病例设计3个治疗计划:①基于第1次CT图像对疗程一设计的治疗计划;②基于第2次CT图像对疗程二设计的治疗计划;③基于两次CT图像的融合图像对全疗程设计的治疗计划。用两种方法对危及器官受照剂量进行评估:①将疗程一计划和疗程二计划的评估结果进行横向和纵向相加;②对基于融合图像设计的计划直接进行全疗程受量评估。然后将两种方法的评估结果进行对比。结果:将利用两组图像分别设计的治疗计划的评估结果进行纵向和横向相加与利用融合图像对整个疗程危及器官的受量直接进行评估的结果比较,多项指标有相关性(P<0.05)。结论:在放疗过程中更改治疗计划时采用CT/CT图像融合技术,可使计划评估结果更加直接、准确,能够更好的指导临床治疗。
Objective: To explore the application of CT/CT image fusion in evaluation of non-small cell lung cancer(NSCLC) radiotherapy plans. Methods: Eleven NSCLC cases for 3-D conformal radiation therapy were selected for CT scanning before and during the treatment. Three treatment plans were designed for each case based on: ①the original images for the first course; ②the second-time images for the second course; ③the fusion images for the whole course. The images for the first two treatment plans and the second plan were evaluated and compared. Results: After evaluation, the treatment plan based on the ones acquired in the first and second course had distinct difference with that based on the fusion images for the whole course (P〈0.05). Conclusion: It is more direct and accurate to evaluate the plan when the plan is changed during the treatment course using the image fusion technique.
出处
《武汉大学学报(医学版)》
CAS
2007年第5期638-641,F0002,共5页
Medical Journal of Wuhan University
基金
湖北省科技攻关项目(编号:2007A301B33)
关键词
图像融合技术
放射疗法
治疗计划评估
非小细胞肺癌
Image Fusion Technique
Radiation Therapy
Evaluate of Treatment Planning
Non-Small Cell Lung Cancer