摘要
目的研究对接受肠内营养的慢性阻塞性肺疾病(COPD)患者应用强化谷氨酰胺的效果。方法 68例慢性阻塞性肺疾病患者,依据使用肠内营养制剂不同分为观察组和对照组,每组34例。对照组接受常规肠内营养,观察组在对照组基础上接受强化谷氨酰胺肠内营养,比较两组临床效果。结果两组治疗前转铁蛋白(TRF)、前白蛋白(PA)、白蛋白(Alb)水平比较差异无统计学意义(P>0.05);治疗后两组各项指标均较治疗前有所升高,且观察组高于对照组,差异具有统计学意义(P<0.05)。治疗前两组丙二醛(MDA)、谷胱甘肽过氧化物酶(GSH-PX)、超氧化物歧化酶(SOD)水平比较差异无统计学意义(P>0.05);治疗后观察组MDA(4.13±1.29)mmol/L明显低于对照组(5.44±1.59)mmol/L,GSH-PX(197.57±6.88)U/ml、SOD(77.38±3.16)U/ml明显高于对照组(176.6±10.28)U/ml、(64.29±5.30)U/ml,差异具有统计学意义(P<0.05)。结论对接受肠内营养的慢性阻塞性肺疾病患者应用强化谷氨酰胺,能够使患者营养状况得到明显改善,加快患者康复,可进行推广。
Objective To study the effect of enhanced glutamine enteral nutrition in patients with chronic obstructive pulmonary disease（COPD）.Methods A total of 68 patients with chronic obstructive pulmonary disease were divided by different enteral nutrition preparations into observation group and control group,with 34 cases in each group.The control group received conventional enteral nutrition,and the observation group received enhanced glutamine enteral nutrition on the basis of the control group.The clinical effect in two groups was compared.Results Before treatment,both groups had no statistically significant difference in transferrin（TRF）,prealbumin（PA）,albumin（Alb） levels（P〈0.05）.After treatment,both groups had higher indicators than before treatment,and the observation group had higher ascending range than the control group.Their difference was statistically significant（P〈0.05）.Before treatment,both groups had no statistically significant difference in malondialdehyde（MDA）,glutathione peroxidase（GSH-PX） and superoxide dismutase（SOD）（P〉0.05）.After treatment,the observation group had obviously lower MDA as（4.13±1.29） mmol/L than（5.44±1.59） mmol/L in the control group,and obviously higher GSH-PX as（197.57±6.88） U/ml,SOD as（77.38±3.16） U/ml than（176.6±10.28） U/ml and（64.29±5.30） U/ml in the control group.Their difference was statistically significant（P〈0.05）.Conclusion Application of enhanced glutamine enteral nutrition in patients with chronic obstructive pulmonary disease can obviously improve the nutritional status of the patients and accelerate their recovery.It can be promoted.
作者
靳峰妮
JIN Feng-ni.(Department of Clinical Nutrition, Shanxi Yuncheng Central Hospital, Yuncheng 044000, Chin)
出处
《中国实用医药》
2018年第7期101-103,共3页
China Practical Medicine
关键词
慢性阻塞性肺疾病
肠内营养
强化谷氨酰胺
Chronic obstructive pulmonary disease
Enteral nutrition
Enhanced glutamine
