摘要
肝内胆管细胞癌(ICC)是起源于胆管上皮细胞组织的原发性肿瘤,近年来全世界发病率呈上升趋势,已成为肝脏第二大常见恶性肿瘤,仅次于肝细胞肝癌。ICC起病隐匿,临床表现缺乏特异性,大多数患者确诊时已处于晚期,影响治疗及预后,因此及时诊断和治疗至关重要。根治性治疗方案主要为外科手术切除,其它治疗方案包括全身化疗、局部消融、经导管动脉化疗栓塞(TACE)、^(90)Y栓塞、^(125)I粒子植入等。本文主要介绍ICC诊断及治疗进展。
Intrahepatic cholangiocellular carcinoma（ICC） is a primary tumor originating from the epithelial cells of bile duct. In recent years, incidence of ICC in the world is on the rise, and it has become the second common malignant tumors of the liver, with its incidence being next only to hepatocellular carcinoma（HCC）. The onset of ICC is insidious, its clinical manifestations are lack of specificity, most of the patients are already in the advanced stage when the diagnosis is confirmed, thus, affecting the treatment and prognosis. Therefore, early diagnosis and treatment is essential. The radical treatment plan is mainly surgical excision, and other treatment options include systemic chemotherapy, local ablation, transcatheter arterial chemoembolization（TACE）, selective intraarterial radiotherapy with yttrium-90 microspheres（SIRT-^（90）Y）,^（125）I seed implantation, etc. This article aims to make a comprehensive introduction about the recent advances in the diagnosis and treatment of ICC.
出处
《介入放射学杂志》
CSCD
北大核心
2018年第3期285-289,共5页
Journal of Interventional Radiology
基金
江苏省临床医学科技专项项目(BL2013029)
关键词
肝内胆管细胞癌
诊断
手术治疗
局部治疗
intrahepatic cholangiocellalar carcinoma
diagnosis
surgical resection
local treatment
