摘要
肝内胆管细胞癌(ICC)是少见的原发性肝癌之一,其发病机制尚不明确,早期无明显临床症状,诊断困难,多数患者在就诊时已是中晚期,失去手术机会。ICC恶性程度高且缺乏标准、有效、个体化的治疗方案,预后往往较差。不同医师对该病的诊治策略不尽相同,手术指征的把握存在分歧。本文结合国内外文献,对ICC的分期方法、诊断步骤、术式选择及非手术治疗方法的进展作一综述,旨在提高对该疾病的认知,避免在临床工作中发生误诊及漏诊,治疗过度或不足的情况,让患者获益最大化。
Intrahepatic cholangiocarcinoma(ICC)is a rare primary liver cancers.The pathogenesis is obscure and usually,it is asymptomatic in early stage,the diagnosis is made with difficulty.Most patients are in advanced stage upon diagnosis and have unresectable tumors.Strategies and indications for surgery are variable by different doctors.Standard,effective and individualized treatment strategies are lacking,with high malignancy,the tumor often shows unfavorable prognosis.In this review,we elucidate the cancer staging system,diagnostic algorithm,choice of surgical approaches and progress of nonsurgical treatment in conjunction with domestic and foreign literatures,so as to enhance the awareness of ICC and avoid misdiagnosis or underdiagnosis,eccessive or inadequate treatment in clinical work and confer benefit to patients.
作者
王光宇
胡明华
陈光彬
Wang Guangyu;Hu Minghua;Chen Guangbin(Wannan Medical College,Wuhu 241000,China;Department of Hepatobiliary Surgery,the Second People′s Hospital of Wuhu,Wuhu 241000,China)
出处
《国际外科学杂志》
2020年第2期127-130,共4页
International Journal of Surgery
关键词
胆管肿瘤
诊断
治疗应用
肝内胆管细胞癌
Bile duct neoplasms
Diagnosis
Therapeutic uses
Intrahepatic cholangiocarcinoma
