摘要
目的探讨术前MRI对肝细胞癌（HCC）术后复发及转移的预测价值。方法回顾性分析2013年6月至2014年6月在本院行根治性切除的85例HCC患者的术前临床及影像学征象,并进行为期2年的随访,随访内容为复发和转移。比较病史资料及MRI征象（肿瘤位置、最大径、边缘、包膜以及液化区）与HCC术后复发和转移的关系。结果随访的85例HCC患者有25例出现术后复发和/或转移,单因素分析结果显示,术后复发阳性与阴性组比较,年龄、性别、长期饮酒史、肝硬化、AFP、TKI、分化程度、Ki67及肿瘤位置、最大径、液化区在两组间均无统计学差异（均P〉0.05）,结节形态、包膜在两组间差异具有统计学意义（均P〈0.05）;二分类Logistic分析显示,仅结节形态与HCC的复发和转移相关（OR=5.92,P〈0.05）。结论术前MRI瘤灶结节形态是HCC复发和转移的预测因素,在临床上应引起注意。
Objective To investigate the predictive value of preoperative MRI in the recurrence and metastasis of hepatocellular carcinoma（ HCC）. Methods the clinical and imaging features of 85 patients with HCC who underwent radical resection from June 2013 to June 2014 in our hospital were analyzed retrospectively. The patients were followed up for 2 years. The relationship between recurrence and metastasis of HCC after operation was analyzed by comparing the data of medical history and MR imaging findings（ tumor location,maximum diameter,shape,capsule,liquefaction area and margin of tumor tissue）. Results 85 cases of HCC patients were followed up with 25 cases of postoperative recurrence and/or metastasis. The results of univariate analysis showed that post-operative recurrence of positive and negative groups,age,sex,long-term drinking history,liver cirrhosis,AFP,TKI,Ki67 and the degree of differentiation,tumor location,had no significant difference between the maximum size and liquid the area of tumor tissue,edge enhancement between the two groups（ P〉0. 05）. Tumor morphology and capsule had statistical significance in the difference between the two groups（ P 〈0. 05）. Two Logistic classification analysis showed only tumor morphology and HCC recurrence and metastasis（ OR =5. 92,P〈0. 05）. Conclusion preoperative MRI tumor morphology is a predictor of recurrence and metastasis of HCC,and should be recognized in clinical practice.
出处
《临床放射学杂志》
CSCD
北大核心
2018年第2期267-270,共4页
Journal of Clinical Radiology
基金
广西壮族自治区卫生和计划生育委员会自筹经费科研课题(编号:Z2016476)
关键词
肝细胞癌
术后复发/转移
预测
Hepatocellular carcinoma Postoperative recurrence/metastasis Prediction
