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阿司匹林联合硫酸氢氯吡格雷口服治疗脑梗死的临床疗效分析 被引量:13

Analysis of clinical efficacy of aspirin and oral clopidogrel bisulfate in the treatment of cerebral infarction
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摘要 目的分析阿司匹林联合硫酸氢氯吡格雷口服治疗脑梗死的临床疗效。方法 88例脑梗死患者,随机分为对照组和观察组,每组44例。对照组患者采用阿司匹林治疗,观察组患者采用阿司匹林联合硫酸氢氯吡格雷治疗。对比两组临床治疗效果。结果观察组治疗总有效率为95.45%,优于对照组的68.18%,差异具有统计学意义(P<0.05)。治疗前两组美国国立卫生研究院卒中量表(NIHSS)评分对比,差异无统计学意义(P>0.05)。治疗后两组NIHSS评分均低于治疗前,且观察组低于对照组(P<0.05)。结论脑梗死患者联合应用阿司匹林联合硫酸氢氯吡格雷治疗的效果显著,值得推广。 Objective To analyze the clinical efficacy of aspirin and oral clopidogrel bisulfate in the treatment of cerebral infarction. Methods A total of 88 cerebral infarction patients were randomly divided into control group and observation group, with 44 cases in each group. The control group received aspirin for treatment, and the observation group received aspirin and clopidogrel bisulfate for treatment. The clinical treatment effect in two groups was compared. Results The observation group had better total treatment effective rate as 95.45% than 68.18% in the control group, and the difference was statistically significant(P〈0.05). Before treatment, both groups had no statistically significant difference in National Institutes of Health Stroke scale(NIHSS) score(P〉0.05). After treatment, both groups had lower NIHSS score than before treatment, and the observation group was lower than the control group(P〈0.05). Conclusion Combination of aspirin and clopidogrel bisulfate shows significant effect in treating cerebral infarction patients and worthy of promotion.
出处 《中国实用医药》 2018年第3期71-73,共3页 China Practical Medicine
关键词 阿司匹林 硫酸氢氯吡格雷 脑梗死 临床疗效 Aspirin Clopidogrel bisulfate Cerebral infarction Clinical efficacy
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