摘要
目的:观察早期亚低温联合尼莫地平治疗脑出血后缺血性脑损害的临床疗效。方法:收治脑出血患者120例,随机分两组。入院后均给予常规脑出血治疗,给予亚低温治疗。治疗组在以上治疗基础上给予尼莫地平静脉滴注。治疗1周测定两组颈内静脉的血氧饱和度、乳酸及外周血中SOD、MDA。治疗3个月后随访,采用ADL量表对患者的生存质量进行分级。结果:治疗组血氧饱和度、SOD高于对照组(P<0.05),乳酸、MDA低于对照组(P<0.05)。治疗3个月两组生存质量分级比较,治疗组明显优于对照组,差异有统计学意义(P<0.05)。结论:早期亚低温联合尼莫地平疗法能有效改善脑出血患者缺血性脑损害症状,提高其生存质量。
Objective：To observe the effect of early mild hypothermia combined with nimodipine on ischemic brain damage after intracerebral hemorrhage.Methods：120 patients with cerebral hemorrhage were selected.They were randomly divided into the two groups.The treatment of routine cerebral hemorrhage was given after admission and mild hypothermia was given.The treatment group was given nimodipine intravenous drip on the basis of the above treatment.The blood oxygen saturation,lactic acid and SOD and MDA in the peripheral blood of the internal jugular vein were measured at 1 week.After 3 months of follow-up,the ADL scale was used to classify the patient＇s quality of life.Results：The blood oxygen saturation and SOD in the treatment group were higher than those of the control group（P〈0.05）;lactic acid and MDA were lower than the control group（P〈0.05）.There was significant difference in the grade of quality of life of the two groups after 3 months of treatment（P〈0.05）,and the treatment group was obviously superior to the control group.Conclusion：Early mild hypothermia combined with nimodipine can effectively improve the symptoms of ischemic brain damage and improve the quality of survival in patients with cerebral hemorrhage.
出处
《中国社区医师》
2018年第7期82-82,84,共2页
Chinese Community Doctors
关键词
亚低温治疗
尼莫地平
脑出血
缺血性脑损害
Mild hypothermia
Nimodipine
Cerebral hemorrhage
Ischemic brain damage
