摘要
目的比较前段光学相干断层扫描仪(AS-OCT)、Lenstar、超声生物显微镜(UBM)测量中央角膜厚度(CCT)的差异性、相关性、一致性。方法采用横断面研究,纳入2015年10月到2016年8月于中国医科大学附属第四医院就诊的患者54例(83眼),按顺序行Lenstar、AS-OCT、UBM检查,测量CCT。差异性采用随机区组方差分析,相关性采用Pearson相关分析,一致性采用Bland-Altman分析。结果 3种仪器的CCT测量结果有明显差异(P<0.05),两两比较差异有统计学意义(均P<0.05),3种仪器的CCT测量结果有显著相关性(均P<0.001)和良好的一致性。结论 AS-OCT、Lenstar、UBM的CCT测量结果有良好一致性和高度相关性,在某些情况下可以相互替代。AS-OCT可作为青光眼早期筛查、判断CCT厚度的首选。
Objective To compare the differences,correlation,and consistency among central corneal thickness （CCT） measure- ments by anterior segment optical coherence tomography （AS-OCT） ,Lenstar,and ultrasound biomicroscopy （UBM）. Methods In this cross-sectional study,AS-OCT,Lenstar,and UBM were used to measure the CCT in 54 patients （83 eyes） between October 2015 and Au- gust 2016 in the Fourth Affiliated Hospital of China Medical University. Data were statistically analyzed by random analysis of variance, Pearson correlative analysis, and Bland-Ahman analysis to compare the difference, correlation, and consistency among the three instru- ments. Results The differences in the mean CCT measured by the three instruments were statistically significant （P 〈 0.05 for all com- parisons）. There was also a high correlation （all P 〈 0.001 ） and consistency among the three instruments. Conclusion There is a high level of correlation and consistency in the CCT measurements by the three instruments. Therefore, these could be interchangeable under some circumstances. AS-OCT could be the first choice as an early screening tool for glaucoma.
出处
《中国医科大学学报》
CAS
CSCD
北大核心
2018年第2期123-127,共5页
Journal of China Medical University
基金
辽宁省自然科学基金(2014021005,201602851)
关键词
前段光学相干断层扫描仪
原发性闭角型青光眼
中央角膜厚度
anterior segment optical coherence tomography
primary angle closure glaucoma
central corneal thickness
