摘要
目的:观察半夏厚朴汤加减治疗甲状腺结节的临床疗效。方法:将120例甲状腺结节患者随机分为对照组和治疗组,每组各60例。对照组给予左旋甲状腺素,治疗组在对照组的基础上给予半夏厚朴汤加减,观察两组患者的临床疗效,比较两组患者治疗前后临床症状积分和最大甲状腺结节直径变化情况,检测两组患者治疗前后促甲状腺激素(thyroid stimulating hormone,TSH)水平。结果:对照组有效率为63.33%,治疗组有效率为86.67%,两组患者临床疗效比较,差异具有统计学意义(P<0.05)。两组患者治疗后临床症状积分低于治疗前,且治疗组低于对照组,差异具有统计学意义(P<0.05)。两组患者治疗后TSH水平与治疗前无显著性差异,治疗组与对照组比较,差异亦无统计学意义(P>0.05)。两组患者治疗后最大甲状腺结节直径明显小于治疗前,且治疗组小于对照组,差异具有统计学意义(P<0.05)。结论:半夏厚朴汤加减治疗甲状腺结节临床疗效显著,可改善患者临床症状,减小甲状腺结节直径。
Objective：To observe tile clinical curative effect of Pinellia and Officinal Magnolia Bark Decoction on thyroid nodule thyroid nodule （TN）. Methods：One hundred and twenty patients with TN were randomly divided into the control group and the treatment group,with 60 cases in each group. The ones in the control group were given levothyroxine for treatment,while the ones in the treatment group were added Pinellia and Officimd Magnolia Bark Decoction based on the treatment of the conlrol group. Then the two groups＇ clinical curative effects were observed. The clinical symptom score and the maximum thyroid nodule diameter in the two groups before and after treatment were compared. The levels of thyroid stimulating hormone （TSH） in the two groups before and after treatment were detected. Resuhs：The effective rate in the control group was 63.33% ,while that in the treatment group was 86.67% , and the differenee between the two groups was statistically significant （P 〈 0.05）. The clinical symptom scores of the two groups were lower than those beibre the treatment,and the treatment group was lower than the control group. The difference was statistically significant （ P 〈 0.05 ）. In terms of TSH level, there was no significant difference between the two groups after treatment and before treatment. There was no significant difference in TSH between the lrealment group an〈] the co^- trol group, either （P 〉 0.05 ）. The diameters of the maximum thyruid nodule after the treatment in the two groups were significant- ly smaller than those beh^re the treatment,and the treatment group was less than the control group. The difference was statistically significant （P 〈 0.05）. Conclusion：Pinellia and Offieinal Magnolia Bark Decoction has a remarkable clinical curative effect on TN ,can improve the clinical symptoms of the patients and reduce the diameter of thyroid nodules.
出处
《河南中医》
2018年第1期48-50,共3页
Henan Traditional Chinese Medicine
基金
河南省中医药科学研究专项课题(编号:2015ZY-02084)
关键词
甲状腺结节
半夏厚朴汤
左旋甲状腺素
促甲状腺激素
张仲景
《金匮要略》
thyroid nodule （ TN ）
Pinellia and Officinal Magnolia Bark Decoetion
levothyroxine
thyroid slimulating hormone （ TSH ）
Zhang Zhong-jing
Essentials from the Golden Cabinet
