摘要
目的调查和分析常年定期献血人群血栓性疾病的发生情况跟踪随访结果。方法选取2008年2月至2012年2月常年定期献血者800例和同期体检的与其人口学特征相近的未参与献血或非常年定期献血者500例,定义为固定献血组(n=800)和非固定献血组(n=500)。另收集2014年5月至2015年5月期间来院咨询的300例意向献血者的临床资料,采用随机双盲法分为研究组(n=150)和对照组(n=150),研究组根据本次跟踪随访结果给予针对性健康宣教,对照组健康宣教不公布本次跟踪随访结果。跟踪随访固定献血组和非固定献血组人群2年内血栓性疾病及其他相关疾病的发生情况,调查和统计研究组和对照组献血情况差异。结果固定献血组血栓性疾病及相关疾病发生率10.88%显著低于非固定献血组19.60%(P<0.05)。研究组总献血率69.33%明显高于对照组54.00%(P<0.05)。研究组献血量300 ml、400 ml、2次以上累计>400 ml的人群占比均明显高于对照组,两组献血量分布比较有统计学意义(P<0.05)。结论常年定期性献血可降低献血人群血栓性疾病及相关疾病的发生风险,其可显著提高意向献血人群献血率和献血量。
Objective To investigate and analyze the effect of follow-up results of the incidence of thrombotic diseases in regular blood donors on the rate of blood donation in potential donors. Methods From February 2008 to February 2012,800 regular blood donors and 500 donors who have the same medical and demographic characteristics or did not participate in regular blood donation were included in the regular blood donation group （ n = 800 ） and irregular blood donation group （ n = 500 ）. The clinical data of 300 potential donors from May 2014 to May 2015 were collected and randomly divided into the study group （n = 150 ）and the control group（ n = 150）by double blind method. According to the follow-up results, the study group was given targeted health education, and the control group was not informed of the follow-up results. The incidence of thrombotic disease and other related diseases within 2 years were followed up, and the status of blood donation was compared between the study group and the control group. Results The incidence rate of thrombotic disease and other related diseases in the regular blood donation group（ 10. 88% ）was significantly lower than that in the irregular blood donation group （ 19.60% ） （ P 〈 0. 05 ）. The total rate of blood donation in the study group （69.33%）was significantly higher than that in the control group （54.00%） （P 〈 0. 05 ）. In the study group, the proportions of donors who donated 300 ml, 400 ml and more than twice the amount of blood donation 〉 400 ml were significantly higher than those in the control group （ P 〈 0. 05 ）. Conclusion Regular blood donation can reduce the risk of thrombotic diseases and related diseases, which can significantly improve the blood volume donated by potential donors.
出处
《血栓与止血学》
2017年第5期780-782,共3页
Chinese Journal of Thrombosis and Hemostasis
