摘要
目的探讨猪肺磷脂注射液治疗新生儿重症胎粪吸入性肺炎的临床疗效。方法收集我院2016年3月—2017年4月64例重症胎粪吸入性肺炎新生儿,按照就诊顺序分成观察组与对照组,对照组患儿采用常规方法予以治疗,观察组在此基础上应用猪肺磷脂注射液,观察2组治疗前后血气变化及使用呼吸机时间、吸氧时间、住院时间。结果观察组治疗后2 h、12 h、24 h的PaO_2、PaO_2/FiO_2与对照组相比较均提高(P<0.05);观察组使用呼吸机时间、吸氧时间、住院时间与对照组比较均减少(P<0.05)。结论猪肺磷脂注射液治疗新生儿重症胎粪吸入性肺炎具有较为明显的临床效果,可改善新生儿氧合情况,促进恢复。
Objective To evaluate the clinical efficacy of Poractant Alfa Injection in neonates with meconium aspiration pneumonia. Methods From March 2016 to April 2017, 64 cases of severe meconium aspiration pneumonia of newborn, randomly divided into observation group and control group, the control group were treated with conventional methods, the observation group based on the application of poractant alfa injection, 2 groups were observed before and after treatment of blood gas changes and ventilator time, oxygen time, hospitalization time. Results After treatment, the PaO2 and PaO2/FiO2 of 2 h, 12 h and 24 h in the observation group were increased compared with the control group （P 〈 0.05）; The observation group using breathing machine time, oxygen inhalation time, length of hospital stay compared with the control group were reduced （P〈 0.05）. Conclusion Poractant alfa injection treatment of newborns with severe meconium aspiration pneumonia has obvious clinical effect, can signifcantly improve the neonatal oxygenation, promote recovery.
出处
《中国继续医学教育》
2017年第24期157-158,共2页
China Continuing Medical Education
