摘要
目的探讨肺表面活性物质在新生儿重症肺炎治疗中的应用价值。方法选取我院收治的94例新生儿重症肺炎患儿进行研究,将其随机分为两组,对照组47例,实施常规机械通气治疗,观察组47例,在机械通气的同时行肺表面活性物质治疗,对比两组治疗效果。结果治疗后,两组患者在氧合指数(OI)、动脉/肺泡氧分压比值(a/APO2)、血清及支气管肺泡灌洗液中SP-B水平方面差异均存在统计学意义(P<0.05);且观察组患者机械通气时间及氧暴露时间均短于对照组(P<0.05)。结论对新生儿重症肺炎患儿实施肺表面活性物质治疗效果显著。
Objective To investigate the application of pulmonarysurfactant in the treatment of severe pneumonia in neonates.Methods 94 cases of neonatal severe pneumonia in our hospitalwere studied, which were randomly divided into two groups,47 cases in the control group were treated with conventionalmechanical ventilation therapy, observation group of 47 caseswere treated with mechanical ventilation and pulmonary surfactanttherapy, treatment effect of two groups compared. Results Aftertreatment, oxygen index （OI）, arterial / alveolar oxygen ratio （a/APO2）, SP-B level of serum and bronchoalveolar lavage fluidbetween two groups had significant difference （P 〈0.05）; and themechanical ventilation time and the exposure time in observationgroup were significantly shorter than the control group （P 〈0.05）.Conclusion The effect of pulmonary surfactant on neonate severepneumonia is significant.
出处
《中国卫生标准管理》
2017年第24期47-48,共2页
China Health Standard Management
关键词
肺表面活性物质
新生儿重症肺炎
机械通气
pulmonary surfactant
severe pneumonia in neonates
mechanical ventilation
