摘要
目的探讨盐酸氨溴索雾化吸入辅助治疗新生儿肺炎的临床效果及对动脉血气的影响。方法选择2014年12月至2015年12月本院诊治的120例肺炎新生儿为研究对象,按照随机数表法将其分为观察组(60例)和对照组(60例)。对照组患儿常规使用抗生素,结合吸氧、静脉滴注盐酸氨溴索治疗,观察组患儿在对照组治疗基础上辅以盐酸氨溴索雾化吸入治疗。观察两组患儿治疗前后动脉血气变化、各临床症状消失时间、住院时间以及临床疗效。结果治疗后,观察组患儿动脉血氧分压(Pa O2)高于对照组(P<0.05),动脉血二氧化碳分压(Pa CO2)低于对照组(P<0.05),临床症状消失时间、住院时间均短于对照组(P<0.05),显效率高于对照组(P<0.05)。结论盐酸氨溴索雾化吸入辅助治疗新生儿肺炎效果显著,可明显改善动脉血气结果,促进患儿早日康复。
Objective To investigate the clinical effects of ambroxol hydrochloride atomizing inhalation in the treatment of neonatal pneumonia and its effect on arterial blood gas. Method 120 cases of neonate with pneumonia from December 2014 to December 2015 in our hospital were selected as subjects of study, and they were divided into observation group（60 cases） and control group（60 cases） according to a random number table method. Control group neonate were given conventional antibiotics, inhaling oxygen and intravenous ambroxol hydrochloride, observation group neonate were given ambroxol hydrochloride atomizing inhalation as adjunctive therapy on the basis of control group. Arterial blood gas changes, duration of clinical symptoms, length of stay and clinical efficacy before and after treatment were compared between the two groups. Result After treatment, Pa O2 of observation group was higher than control group（P〈0.05）, Pa CO2 was lower than control group（P〈0.05）, duration of clinical symptoms, length of stay of observation group were shorter than control group（P〈0.05）, the effective rate and obvious effective rate of observation group were higher than control group（P〈0.05）. Conclusion The effect of ambroxol hydrochloride atomizing inhalation in the treatment of neonatal pneumonia is significant, it can improve the arterial blood gas significantly and promote the early recovery of neonate.
出处
《中国医学前沿杂志（电子版）》
2016年第8期96-99,共4页
Chinese Journal of the Frontiers of Medical Science(Electronic Version)
关键词
盐酸氨溴索
新生儿肺炎
动脉血气分析
Ambroxol hydrochloride
Neonatal pneumonia
Arterial blood gas analysis
