摘要
目的探讨翼状胬肉切除联合自体角膜缘干细胞移植术的临床效果。方法随机选取我科室2014年1月至2016年10月收治的300例翼状胬肉患者(336眼),按照治疗方法的不同分为研究组与对照组,研究组150例(167眼)采取翼状胬肉切除联合自体角膜缘干细胞移植术进行治疗,对照组150例(169眼)采取翼状胬肉单纯切除术进行治疗,观察比较两组患者手术角膜创面愈合时间、治愈率、复发率和不良反应发生情况。结果研究组患者的角膜创面愈合时间、复发率优于对照组,而治愈率高于对照组,差异均具有统计学意义(P<0.05);两组均无严重的不良反应发生。结论翼状胬肉切除联合自体角膜缘干细胞移植术具有较高的治愈率,术后不良反应较少,复发率低,是一种安全有效的治疗方法。
Objective To explore the clinical effecl of pterygium excision combined with corneal limbal stem cells aulografl Iransplanlalion. Methods Three hundred cases of pterygium patients （336 eyes） admitted in our department from Jannuary 2014 lo October 2016 were selected and divided into research group and control group according lo different treatment methods. The 150 palienls （167 eyes） in lhe research group received pterygium excision combined corneal limbal stem cells aulografl transplantation. The 150 palienls （169 eyes） in lhe control group received pterygium resection. The corneal epithelium healing lime, cure rale and recurrence rale, incidence rale of adverse reactions of lhe lwo groups were compared. Results The corneal epithelium healing lime and recurrence rale in lhe research group were belter than those of lhe control group, lhe cure rale in lhe research group was higher than lhal of lhe control group, lhe differences were statistically significant （P 〈0.05）. There were no serious adverse events in both groups. Conclusion Pterygium excision combined with corneal limbal stem cells aulografl transplantation is a kind of safe and effective therapeutic method with high cure rale, less adverse reactions and lower recurrence rale.
出处
《临床医学研究与实践》
2017年第18期76-77,共2页
Clinical Research and Practice
关键词
翼状胬肉切除
自体角膜缘干细胞
移植
pterygium excision
corneal limbal stem cells aulografl
transplantation
