摘要
目的探讨性激素水平对新疆维吾尔族、汉族早期先兆流产患者妊娠结局的影响。方法根据756例先兆流产患者其妊娠结局分为继续妊娠组（汉族256例，维吾尔族261例）和妊娠失败组（汉族124例，维吾尔族115例），测定对比两组患者孕5～8w血清人绒毛膜促性腺激素（β—HCG）、孕酮（P）、雌二醇（E2）水平，并根据自编调查量表进行辩证，分析不同民族先兆流产患者证型构成比。结果汉族中医证型比例由高到低依次为肾虚型（48．56％）、脾。肾两虚型（18％）、血热型（15．34％），血瘀型（6．23％）。维吾尔族患者中医证型比例由高到低依次为血热型（35．37％）、肾虚型（29．12％）、血瘀型（15．68％）、气血虚弱（8．33％）。在孕5、6、7、8w时继续妊娠组β-HCG、P、E2水平较妊娠失败组高（P〈0．05）；维吾尔、汉族相同孕周患者血清β-HCG、P、E2表达差异无统计学意义（P〉0．05）。结论新疆维吾尔族、汉族先兆流产患者中医证型分布不同，血β-HCG、P、E2是预测早期先兆流产结局的可靠指标。
Objective To investigate the effects of serum sex hormone in Uygur and Han ethnic patients with early threatened abortion on pregnancy outcome in Xinjiang.Methods According to pregnancy outcome,756 cases were divided into continuing to pregnancy group（261cases of Uygur vs 256 cases of Han）and pregnancy failure group（115cases of Uygur vs 124 cases of Han）,and serum human chorionic gonadotropin（β-HCG）,progesterone（P）,and estradiol（E2）level at 5-8wof the two groups were compared and dialectically analyzed based on self-scale investigation.And constituent ratio of syndromes were analyzed in the two ethnics.Results Descending order in proportion of TCM syndrome of Han was kidney deficiency（48.56%）,spleen and kidney deficiency（18%）,blood heat（15.34%）and blood stasis type（6.23%）,while that of Uygur was blood heat（35.37%）,kidney deficiency（29.12%）,blood stasis（15.68%）,blood weak type（8.33%）.At 5-8wof pregnant,serum ofβ-HCG,P and E2 levels in continuing pregnancy group were higher than that in pregnancy failure group（P〈0.05）;and at the same gestational age,the levels ofβ-HCG,P,E2 in Uygur and Han patients were no difference（P〉 0.05）.ConclusionDifferent TCM syndromes were distributing in the two ethnics of Xinjiang,β-HCG,P and E2 were reliable indicators for predicting outcome of threatened abortion.
出处
《新疆医科大学学报》
CAS
2016年第7期866-868,872,共4页
Journal of Xinjiang Medical University
基金
新疆维吾尔自治区自然科学基金(2013211A113)
关键词
早期先兆流产
血清人绒毛膜促性腺激素
孕酮
雌二醇
中医证型
early threatened abortion
serum human chorionic gonadotropin
progesterone
estradiol
TCM syndrome
