摘要
目的:探讨无水乙醇+聚桂醇泡沫硬化+平阳霉素+弹力绷带联合应用治疗儿童静脉畸形的临床疗效和安全性。方法:选取2013年6月—2016年6月在我院治疗的临床诊断为静脉畸形的患儿188例,根据puig’s分型分为4型,其中Ⅰ型48例,Ⅱ型58例,Ⅲ型52例,Ⅳ型30例,联合应用无水乙醇、聚桂醇泡沫硬化、平阳霉素、弹力绷带进行治疗。术后1个月复查。结果:188例患儿,平均每例治疗3次,其中98例治愈,70例病情改善,20例有效控制病情,13例术后疼痛,3例术后破溃,不良反应发生率为8.5%(16/188)。结论:联合应用无水乙醇+聚桂醇泡沫硬化+平阳霉素+弹力绷带的方法治疗静脉畸形是安全、有效的。
Objective： To investigate the safety and efficacy of combination therapy with ethanol＋foam sclerotherapy＋bleomycin A5 ＋ medical elastic sleeve for venous malformation in children. Methods： During the period of June 2013 to June 2016, a total of 188 children with venous malformations in Hebei Children’s Hospital were selected and divided into four types according to puig’s classification, such as type I 48 cases, type n 58 cases, type IE 52 cases and type IV 30 cases, and the patients were treated with combination therapy of ethanol, foam sclerotherapy, bleomycin A5 and medical elastic sleeve. The treatment results and complications were recorded and evaluated after one month. Results ： The 188 children were averagely treated for three times, among which 98 cases were cured, 70 cases were improved, 20 cases were validly controlled , 13 cases had postoperative pain , and 3 cases had postoperative rupture . The adverse reaction rate was 8.5% （16/188）. Conclusion： Combination therapy of ethanol ＋ foam sclerotherapy ＋bleomycin A5＋medical elastic sleeve for venous malformation is an effective and safe therapy.
出处
《中华介入放射学电子杂志》
2017年第4期227-230,共4页
Chinese Journal of Interventional Radiology：electronic edition
关键词
静脉畸形
硬化治疗
乙醇
聚桂醇
平阳霉素
儿童
Venous malformations
Sclerotherapy
Ethanol
Sclerotherapy
Bleomycin A5
Children
