摘要
目的探讨DSA导引下经皮硬化治疗儿童阴茎区静脉畸形的效果和安全性。方法回顾性分析2016年1月至2017年6月山东大学齐鲁儿童医院采用经皮穿刺硬化治疗的11例阴茎区静脉畸形患儿临床资料。DSA透视下行局部静脉造影,判断瘤巢形态、范围和引流静脉回流情况。根据造影流速情况选择硬化剂(平阳霉素或聚多卡醇),DSA监视下经皮注射治疗。术后1个月复查MRI,显示仍有残留病灶予重复治疗。每次治疗后记录不良反应,随访评价疗效。结果 11例患儿14处病灶共接受32次硬化治疗,平均(2.5±1.0)次/例。随访24个月,6例治愈,3例症状明显缓解,2例部分缓解,均无复发或进展。所有患儿均未出现溃破、出血、感染及功能障碍等严重并发症。结论 DSA引导经皮硬化治疗儿童阴茎区静脉畸形安全有效,不影响阴茎外观和功能,值得临床推广。
Objective To investigate the efficacy and safety of DSA-guided percutaneous sclerotherapy in treating venous malformations at penile area in children. Methods The clinical data of 11 sick children with penile venous malformations,who were admitted to the Qilu Children’s Hospital of Shandong University of China during the period from January 2016 to June 2017 to receive percutaneous sclerotherapy under general anesthesia,were retrospectively analyzed. Under DSA fluoroscopy,local venography was performed to observe the morphology,extent and venous drainage of the tumor nest. According to the velocity of contrast media displayed on DSA fluoroscopy,the pingyangmycin or polydocarol was selected as sclerosing agent,and DSA-guided percutaneous sclerotherapy was carried out. One month after treatment,MRI reexamination was performed,when residual lesions were detected the above treatment was carried out again.The adverse reactions were recorded after each treatment,and the sick children were followed up to evaluate the curative effect. Results A total of 32 interventional sclerotherapy sessions were performed for 14 lesions in11 sick children,with a mean of(2.5 +1.0) sessions per case. The sick children were followed up for 24 months,complete cure was achieved in 6 sick children,obvious improvement of clinical symptoms in 3,and partial remission in 2. No recurrence or progression of disease occurred. No serious complications such as ulceration,hemorrhage,infection or functional disorder occurred in all sick children. Conclusion For the treatment of venous malformations at penile area in children,DSA-guided percutaneous sclerotherapy is safe and effective. This treatment does not affect the appearance and function of penis,therefore,it is worthy of clinical promotion.(J Intervent Radiol,2021,30: 18-21)
作者
宋丹
郭磊
李静
王亮
吴长华
张鑫
SONG Dan;GUO Lei;LI Jing;WANG Liang;WU Changhua;ZHANG Xin(Department of Vascular Anomalies and Interventional Radiology,Qilu Children’s Hospital of Shandong University,Jinan,Shandong Province 250022,China)
出处
《介入放射学杂志》
CSCD
北大核心
2021年第1期18-21,共4页
Journal of Interventional Radiology
关键词
硬化治疗
阴茎
儿童
静脉畸形
sclerotherapy
penis
child
venous malformations
