摘要
报告1例皮肤假腺样鳞状细胞癌。患者男,71岁。右侧面部半球形暗红色肿物3个月,迅速增大,无自觉症状。皮肤镜示皮损中央黄白色角化斑片,上覆鳞屑,边缘为白色无结构区,可见毛囊角栓及周围白晕,线状及螺旋状血管。皮损组织病理检查:表皮萎缩,部分缺失,真皮内可见大量上皮样细胞成巢浸润性生长,呈团块及条索状,形成假腺样结构,可见棘层松解细胞以及不典型核分裂象,瘤体间及周围存在混合炎性细胞浸润。诊断:假腺样鳞状细胞癌。
A case of cutaneous adenoid squamous cell carcinoma is reported. A 71-year-old man presented with a rapidly growing, hemispheric, asymptomatic nodule on the right face for 3 months. Dermoscopy showed yellow and white keratinized plaque with white halo, keratin plug, linear and helical blood vessels. Histopathological examination showed epidermal atrophy, invasive growth of epithelioid cells in mass or cord-like pattern, forming pseudoglandular structure, in the dermis. Acantholytic ceils and atypical mitoses were also present. There were mixed inflammatory infiltration in and around the tumor tissue. The diagnosis was adenoid squamous cell carcinoma.
作者
冯华
刘洁
张舒
渠涛
方凯
FENG Hua LIU Jie ZHANG Shu QU Tao FANG Kai(Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China)
出处
《临床皮肤科杂志》
CSCD
北大核心
2017年第11期779-782,共4页
Journal of Clinical Dermatology
关键词
鳞状细胞癌
假腺样
squamous cell carcinoma, adenoid