摘要
目的 探讨临床表现及超声特征对鉴别皮肤鳞状细胞癌(cSCC)和角化棘皮瘤(KA)的诊断价值。方法 回顾性分析经病理证实的33例cSCC与16例KA的临床表现及超声图像特征。结果 cSCC与KA的差异有统计学意义包括以下:(1)病程:cSCC组27例>3个月(87%),KA组14例<3个月(75%),(P=0.000);(2)病变深度:cSCC组平均深度(11.6±6.9)mm,KA组平均深度(6.3±2.8)mm(P=0.005);(3)病变最大径:cSCC组病变最大径(21.6±10.0)mm,KA组病变最大径(14.0±5.8)mm(P=0.007);(4)边界:c SCC组26例边界不清(78.7%),KA组14例边界清楚(87.5%),(P=0.000);(5)形态:c SCC组形态不规则21例(63.6%),KA组形态规则13例(81.2%),(P=0.003)。在年龄、性别、病变部位、累及皮肤层次、内部回声、表皮是否增厚、后方回声、血流情况方面2组数据比较差异无统计学意义(P>0.05)。结论 临床表现联合超声能提高cSCC和KA的临床诊断,并在其治疗和随访中起指导意义。
Objective In order to explore the diagnostic value of clinical manifestations and ultrasound features in differentiating cutaneous squamous cell carcinoma(cSCC) and keratoacanthoma(KA). Methods The clinical manifestations and ultrasound image characteristics of 33 cases of c SCC and 16 cases of KA confirmed by pathology were retrospectively analyzed. Results The differences between skin cSCC and KA had statistical abnormalities including the following:(1)course of disease:27 cases in the c SCC group were more than three months(87%),and 14 cases in the KA group were less than three months(75%),(P=0.000);(2)the depth of the lesion:the average depth of the cSCC group was(11.6±6.9) mm,and the average depth of the KA group was(6.3±2.8) mm(P=0.005);(3)the maximum diameter of the lesion:the maximum diameter of the lesion in the cSCC group was(21.6±10.0) mm,the maximum diameter of the lesion in the KA group was(14.0±5.8) mm(P=0.007);(4)boundary:26 cases in the cSCC group had unclear boundaries(78.7%),and 14 cases in the KA group had clear boundaries(87.5%),(P=0.000);(5)morphology:21 cases(63.6%) were irregular in the cSCC group,13 cases(81.2%) in the KA group were regular(P=0.003). However,on age,gender,lesion location,skin level involved,internal echo,epidermal thickening, back echo,and blood flow,differences between the groups were not statistically significant(P>0.05). Conclusion Clinical manifestations combined with ultrasound can improve the clinical diagnosis of cSCC and KA,and play a guiding role in their treatment and follow-up.
作者
陈燕璇
梁键锋
吴斌洪
罗平平
陈文娟
陈华彬
曾福强
Chen Yanxuan;Liang Jianfeng;Wu Binhong;Luo Pingping;Chen Wenjuan;Chen Huabin;Zeng Fuqiang(Zhongshan Hospital of Traditional Chinese Medicine,Guangzhou University of Chinese Medicine,Zhongshan 528400,China)
出处
《中国中西医结合皮肤性病学杂志》
CAS
2022年第2期122-125,共4页
Chinese Journal of Dermatovenereology of Integrated Traditional and Western Medicine
关键词
皮肤鳞状细胞癌
角化棘皮瘤
临床表现
超声特征
Cutaneous squamous cell carcinoma
Keratoacanthoma
Clinical manifestations
Ultrasound features
