摘要
为了探讨高龄女性利用微刺激方案在助孕治疗周期中添加重组人生长激素(GH)的作用,本中心以84例高龄女性患者为研究对象(研究组加用GH组52例,对照组未加GH组32例),分析比较GH在微刺激方案助孕治疗过程对各项参数的影响。研究结果表明,研究组的促性腺激素(Gn)总用量和Gn使用天数均低于对照组,研究组的HCG日E2值、获卵数、MII数目、2PN数、卵裂期可利用胚胎数均高于对照组,其差异均具有显著性意义(P<0.05);研究组的HCG日宫内膜厚度、受精率、卵裂率、优胚率稍高于对照组,但其差异均无显著性意义(P>0.05)。因此,在微刺激方案中,加用GH对于卵巢低反应的高龄女性患者获益较大。
To investigate the role of adding recombinant human growth hormone（ GH） on older women with mild-stimulus protocol assisted reproduction treatment method,the reproductive center has studied 84 cases of older women（ Research group plus GH,52 cases; Reference group without GH,32 cases）,analyzed and compared the influence of GH on various parameters in the mildstimulus protocol assisted reproduction treatment process. The results show that the total dosages and days of using Gonadotropin（ Gn） of the case group were lower than those of the control group. During the HCG days the levels of female hormone,the eggs obtained,the number of mature oocytes,the two pronucleus,and embryos used in the cleavage phase of the Research group were higher than those of the Reference group. The difference is statistically significant（ P〈0.05）. The thickness of endometrium,the rate of fertilization,the rate of cleavage,and the rate of superior embryo of the Reference group were slightly higher than those of the Reference group.Then there is no significant difference statistically（ P〉0.05）. Therefore,It is more beneficial for older women with low ovarian response that the GH is added in the mild-stimulus protocol assisted reproductive technology.
出处
《医学与哲学（B）》
2017年第9期25-27,共3页
Medicine & Philosophy(B)
关键词
高龄
辅助生殖技术
微刺激方案
生长激素
advanced age
assisted reproductive technology
mild-stimulus protocol
growth hormone
