摘要
目的分析输血前不规则抗体筛查在临床输血中的应用价值.方法选取 2 0 1 5年 6 月- 2 0 1 6年 5 月期间本院 2680例血清标本作为实验对象,均采用微柱凝胶技术进行不规则抗体筛查,根据筛查结果,对输血前不规则抗体筛查的临 床安全意义进行探讨,结果 268 0例中阳性 8 例（ 0 .3 0 %）,女性占比明显高于男性占比,差异具有统计学意义（ P〈0. 05） ; 8 例阳性患者中,特异性抗体 78. 00%,包括抗 -D 33. 33%、抗-E 16. 67%、抗-C 16. 67%、抗-M 33. 3 3% ;非特异性抗体 25. 00%. 结论不规则抗体可导致患者发生溶血性输血反应,对患者生命健康安全造成严重影响,而患者输血前采用微柱 凝胶技术对不规则抗体进行筛查,能够有效预防溶血性输血反应的发生,从而保证患者输血安全.
Objective To analyze the application value of irregular antibody screening before transfusion in clinical transfusion. Methods From June 2015 to May 2016, 2680 serum samples in our hospital were selected as experimental sub-jects. Microcolumn gel technique was employed to screen irregular antibody. According to the screening results？ the clinical safety significance of the irregular antibody screening before transfusion was discussed. Results Among the 2680 cases, 8 cases （0. 30%） were positive, the proportion of female patients was higher than that of male patients, and the difference was statis-tically significant （P〈C0. 05）. Among the 8 positive patients, 78. 00% was the specific antibody, including anti-D 33. 33 % , Anti-E 16. 67% , anti-C 16. 67% , anti-M 33. 33% , and non-specific antibody accounted for 25. 00%. Conclusion Irregular an-tibodies can cause hemolytic blood transfusion reactions in patients, which have a great impact on health and safety of pa-tients. The employment of microcolumn gel technique to screen irregular antibodies before transfusion can effectively prevent the occurrence of hemolytic transfusion reactions, so as to ensure the safety of blood transfusion in patients.
出处
《临床研究》
2017年第9期191-192,共2页
Clinical Research
关键词
输血
筛查
不规则抗体
微柱凝股技术
Blood transfusion
Screening
Irregular antibody
Microcolumn gel technology
