摘要
目的:研究不规则抗体的检测在输血治疗过程中的临床应用价值。方法:采用卡式微柱凝胶法检测2 590例输血患者(观察组)的不规则抗体,分析不规则抗体的分布情况,并以1 346例未进行不规则抗体的输血患者为对照组,比较两组的输血反应发生率。结果:观察组不规则抗体检测阳性率10.03‰(26/2 590),其中抗-E抗体3.86‰、抗-D抗体2.32‰;不规则抗体的产生与妊娠及多次输血有关,行不规则抗体筛查的观察组输血反应发生率为1.16‰,与对照组输血反应发生率3.71‰经卡方检验分析,有统计学差异(P<0.05)。结论:妊娠与多次输血是不规则抗体产生的主要原因之一,输血前不规则抗体的筛查有利于安全用血。
Objective： To study the clinical application value of irregular antibody detection in transfusion therapy. Methods： Detected irregular antibodies in 2 590 patients underwent blood transfusion （Study group） using card micro column gel method, analyzed irregular antibodies distribution. Transfusion reaction rate of those patients were compared with another 1 346 cases that hadn＇t underwent irregular antibodies detection. Results： Positive rate of irregular antibody was 10.03N0 （26/2590） in the observation group, of which the anti-E was 3.86‰, anti-D was 2. 32 ‰. Irregular antibodies were associated with pregnancy and multiple blood transfusions. The observation group blood transfusion reaction rate was 1.16N0, and the control group blood transfusion reaction rate3.71‰, ehi--square analysis revealed signifi- cant difference （P〈0.05）. Conclusion： Pregnancy, multiple blood transfusions are primary causes that produce irregular antibody, and screening of irregular antibody is helpful for the safety of blood transfusion
出处
《海南医学院学报》
CAS
2013年第3期401-403,共3页
Journal of Hainan Medical University
基金
中国高校医学期刊临床专项资金项目(112210568)~~
关键词
不规则抗体
微柱凝胶法
输血
Irregular antibodies
Microeolumn gel method
Blood transfusion
