摘要
银杏叶片提取物对多种疾病具有治疗效果,并已被广泛应用于临床实践。黄酮类化合物是银杏叶片提取物的主要活性成分之一,所以研究银杏黄酮的合成途径具有非常重要的意义。该综述首先回顾了植物黄酮生物合成途径的总体研究概况,并介绍了目前已经发现的银杏黄酮合成相关基因;其次,介绍了高通量测序技术在银杏研究中的几个实际应用。另外,作为银杏的重要研究方向之一,该综述讨论了外界条件对银杏细胞、整株及采摘后叶片的黄酮含量及相关基因表达的影响,并着重介绍了笔者实验室的最新实验结果。最后,该综述对银杏黄酮领域未来的研究方向做了展望。
The extract of ginkgo leaves showed positive effects on treatments of many diseases, and has been used clinically world- wide. Considering the fact that flavonoids are the main bioactive components in the extract of ginkgo leaves, it is very important to in- vestigate the flavonoid biosynthesis in ginkgo leaves. In this paper, we first reviewed the research progress of flavonoid biosynthesis in different plants, and introduced the flavonoid biosynthesis related genes discovered in ginkgo. Then, several cases of ginkgo researches using high throughput sequencing technology were described in detail. In addition, as an important research area in ginkgo, the changes of flavonoid content and the expression of corresponding genes were discussed. Specifically, our latest results were described. At last, we prospected the development of research area in flavonoid biosynthesis in ginkgo.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2017年第18期3497-3503,共7页
China Journal of Chinese Materia Medica
基金
杭州市农业自主申报项目(20170432B07)
关键词
银杏
黄酮
基因
Ginkgo biloba
flavonoid
gene
