摘要
目的探究氯己定醇联合含碘手术薄膜对儿童行骨科手术切口感染的影响。方法选取2015年4月-2016年5月于医院接受骨科手术的460例患儿为研究对象,按照随机数表法将所有患儿平均分为两组,每组230例,其中对照组患儿使用含碘消毒液联合含碘手术薄膜进行骨科手术,观察组患儿使用氯己定醇联合含碘手术薄膜进行骨科手术,比较两组患儿术后切口感染率、手术效果、揭开手术薄膜后细菌的阳性率;对发生感染的患儿进行病原菌培养与鉴定,分析病原菌的分布。结果观察组6例患儿发生切口感染,感染率为2.61%,观察组患儿感染人数以及感染率均低于对照组21例(9.13%),差异有统计学意义(χ~2=4.330,P<0.05);观察组患者手术切口薄膜起边率以及手术愈合时间均低于对照组患者,甲级愈合率高于对照组患者,观察组患者揭开手术薄膜后细菌的阳性率低于对照组患者,差异有统计学意义(χ~2=4.116,P<0.05);感染患儿临床送检标本共检测出病原菌67株,其中革兰阴性菌32株、革兰阳性菌27株、真菌6株、其他菌种2株。结论行骨科手术患儿切口感染的主要病原菌是革兰阴性菌,采用氯己定醇联合含碘手术薄膜能够有效降低手术患儿术后的感染率,提高术后恢复效果,对于提高患者的生活质量具有重要作用。
OBJECTIVE To explore the influence of chlorhexidine alcohol combined with iodine-containing surgical film on incision infections in children undergoing orthopedic surgery.METHODS A total of 460 children who received orthopedic surgery in the hospital from Apr 2015 to May 2016 were recruited as the study objects and randomly divided into the two groups,with 230 cases in each group.The children in the control group received the orthopedic surgery by using iodine-containing disinfectant combined with iodine-containing surgical film,while the children in the observation group received the orthopedic surgery by using chlorhexidine alcohol combined with iodine-containing surgical film.The incidence of postoperative incision infections,surgical effects and positive rate of bacteria after uncovering the surgical film were observed and compared between the two groups of children.The culture of pathogens was carried out for the children with infections,the isolated pathogens were identified,and the distribution of pathogens was analyzed.RESULTS Totally 6 children has incision infection in the observation group,with the infection rate 2.61% ;the number of the children with infection and the infection rate were lower in the observation group than in the control group（21,9.13% ）,and there was significant difference（χ^2=4.330,P〈0.05）.The rate of wrinkled edges of surgical film and surgical healing time were lower in the observation group than in the control group,the grade A healing rate of the observation group was higher than that of the control group,and the positive rate of bacteria of the observation group was significantly lower than that of the control group after the surgical film was uncovered（χ^2=4.116,P〈0.05）.A total of 67 strains of pathogens were isolated from clinical submitted specimens of the children with infection,including 32 strains of gram-negative bacteria,27 strains of gram-positive bacteria,6 strains of fungi and 2 strains of other species.CONCLUSION The gram-negative bacteria are domi
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2017年第18期4216-4219,共4页
Chinese Journal of Nosocomiology
关键词
氯己定醇
含碘手术薄膜
骨科手术
感染
病原菌
Chlorhexidine alcohol
Iodine-containing surgical film
Orthopedic surgery
Infection
Pathogen
