摘要
本研究对皮肤常见病─—痤疮４０例病人皮损区的皮肤菌群进行了探讨，并以１０４例健康人面部皮肤菌群及８２例治愈后病人原皮损区菌群分析作为对照，结果痤疮病人皮损区中痤疮丙酸杆菌活菌数为４．５５±０．７３（ＣＦＵ以Ｌｏｇ／ｃｍ２计）。分离率为１００％，表皮葡萄球菌数为４．１９±０．７０（１００％），微球菌数为２．７１±０．６９（６２．５％），杆菌数为３．０９±０．６４（９０％），需氧的革兰氏阴性杆菌数为３．３１±０．７６（３５％），产色素微球菌数为３．０５±０．８２（４５％），痤疮病人皮肤的皮损区内常住菌和过路菌都较健康人明显增加，差异显著（Ｐ＜０．０５或Ｐ＜０．０１）。而经皮肤微生态制剂治疗后痤疮病皮肤菌群与健康人几乎无差异（Ｐ＞０．０５），说明皮肤微生态制剂具有调整皮肤菌群恢复微生态平衡，提高定植抗力的生理作用，故能较有效的治疗痤疮。
Bacterial flora of skin lesion in 40 patients with Acne vuigaris,compared with 104 normal volunteers and 82 curable AcneVulgaris patients The results showed that the number of P.Acnes was 4.55 ± 0.73 (CFU was calculated a5 Log isolation rate was 100%).S. epidermidis 4.19± 0.70(100%),Micrococcus 2.71 ± 0.69(62.5%),Corynebacteria 3.09±0.64(90%).aerobic Gram-negative bacteria 3.13± 0.76(35%),and other micrococco with pigment 3.05± 0.82(45%),Results also showed that the numbers of resident and transient flora were obviously higher in Acne Vulgaris patients thanh tat in normal volunteers(P.<0.05 or P<0.01).The bacterial flora in patients after ecological therapy,however,showed on difference with that in normal volunteers.Our study suggested that ecological therapy was effective to adjust flora to balance to increase colonization resistance.We think they are the mechanisms by which ecological therapy can effectively treat Acne Vulgaris.
出处
《中国微生态学杂志》
CAS
CSCD
1994年第5期9+11-14,11-14,共5页
Chinese Journal of Microecology
关键词
痤疮
皮肤菌群
生态平衡
Acne Vulgaris Bacterial flora of skin Eubiosis
