摘要
目的了解上海某社区老年人群高尿酸血症(hyperuricemia,HUA)患病率及其危险因素,为HUA的社区预防和干预提供信息依据。方法利用检验科实验数据和居民健康档案对2015年度上海市泥城社区≥65岁的5 801名健康体检居民开展横断面调查,探讨影响HUA患病的危险因素,数据分析采用SPSS19.0软件包,以P<0.05为差异有统计学意义。结果横断面调查老年人5 801名,HUA总患病率19.9%,其中65~74岁年龄组,男性患病率为19.6%,高于女性的16.2%,比较差异有统计学意义(χ~2=6.954,P<0.05);≥85岁年龄组,女性患病率为33.6%,高于男性的20.9%,比较差异有统计学意义(χ~2=6.576,P<0.05);不同年龄组HUA患病率比较差异有统计学意义(χ~2=40.344,P<0.05),随着年龄增长,HUA患病率随之升高(趋势χ~2=39.986,P<0.05)。HUA组总胆固醇、甘油三脂、低密度脂蛋白、血肌酐、尿素氮、谷丙转氨酶水平及体重超重或肥胖、高血压患病率均高于尿酸正常组(均P<0.05)。结论上海某社区老年人群HUA患病率较高;老年人HUA与超重或肥胖、高血压、血脂异常、肝功能及肾功能损害关系密切,应针对性开展防治工作。
Objective The purpose of this study was to investigate the prevalence and risk factors of hyperuricemia（HUA） among the elderly population in a community of Shanghai and provide important data for prevention and intervention of HUA in local communities. Methods A total of 5 801 physical examination residents aged no less than 65 in nicheng community of Shanghai in 2015 were investigated with cross-sectional survey. Risk factors about HUA were measured. Data were analyzed using SPSS19.0 software. the difference was statistically significant（P0.05）. Results A total of 5 801 subjects were involved in cross-sectional survey, the total prevalence of HUA was 19.9%. In the group aged 65 to 74, the prevalence was significantly higher in men than in women（19.6% vs. 16.2%; χ-2=6.954; P0.05）. In the group aged no less than 85, the prevalence was significantly higher in women than in men（33.6% vs. 20.9%; χ-2=6.576; P0.05）. Differences between the two groups were statistically significant（χ^2=40.344; P〈0.05）. HUA presenting a trend of increase with the rise in age（Trend test： χ^2=39.986; P〈0.01）. The levels of total cholesterol, triglyceride, low density lipoprotein, serum creatinine, urea nitrogen and alanine aminotransferase were higher in HUA group than in the normal group as well as overweight or obese and hypertension（P〈0.05）. Conclusions The prevalence of HUA were high in the local residents in a Shanghai community. Overweight or obesity, hypertension, dyslipidemia, liver and kidney function damage were closely related to HUA. Thus, it should be targeted to carry out prevention and control work.
出处
《社区医学杂志》
2017年第17期1-3,共3页
Journal Of Community Medicine
基金
上海市浦东新区卫生和计划生育委员会科技发展专项基金资助(PW2015C-17)
关键词
老年人
高尿酸血症
患病率
危险因素
The elderly population
Hyperuricemia
Prevalence
Risk factors
