摘要
目的 :调查上海市打浦桥社区65岁以上体检人群的高尿酸血症患病率,早期发现无症状高尿酸血症患者,分析相关危险因素。方法 :收集2013年上海市打浦桥社区1 540例65岁以上体检人群,其中男680例,女860例,调查高尿酸血症患病率和男、女患病率的差异。同时,按尿酸水平将患者分为高尿酸血症组541例和对照组(无高尿酸血症组)999例,分析导致高尿酸血症的相关危险因素。结果 :高尿酸血症患病率为35.13%(541/1 540),其中男性为35.44%(241/680),女性为34.88%(300/860),差异无统计学意义(P>0.05)。Logistic回归分析发现,高龄、高体质指数、高三酰甘油血症、高肌酐、高尿素氮等为高尿酸血症的危险因素,而血清高密度脂蛋白水平高为保护因素(P均<0.01)。结论 :高尿酸血症与多种代谢疾病相关,老年人高尿酸血症患病率较高。建议65岁以上人群定期测血尿酸水平,及时发现患者并早期干预。
Objective： To investigate the incidence rate of hyperuricemia in the population over 65 years old who had the physical examination in Dapuqiao Community in Shanghai to early find out the patients with asymptomatic hyperuricemia and analyze the related risk factors. Methods： In 2013, 1 540 cases over 65 years old were collected in Dapuqiao Community in Shanghai, among them 680 were the male and 860 the female. The prevalence of hyperuricemia and the differences between the male and female were investigated. At the same time, the patients were divided into a hyperuricemia group with 541 cases and a control group（no hyperuricemia group） with 999 cases according to the level of uric acid and the relative risk factors which caused hyperuricemia were analyzed. Results： The incidence rate of hyperuricemia was 35.13%（541/1 540）, and among them, the male accounted for 35.44%（241/680）, and the female 34.88%（300/860）, and the differences had no statistical significance（P0.05）. The logistic regression analysis found that the old age, high BMI, hypertriglyceridemia, high creatinine, high blood urea nitrogen, and others were the risk factors of hyperuricemia but the high HDL cholesterol level was the protective factor（P0.01）. Conclusion： Hyperuricemia is associated with a variety of metabolic diseases and the elderly people have the high prevalence of hyperuricemia. It is suggested that the regular blood uric acid level be tested for the elderly people over 65 years old to find out the patients and intervene them early.
出处
《上海医药》
CAS
2015年第22期39-42,共4页
Shanghai Medical & Pharmaceutical Journal
关键词
高尿酸血症
患病率
老年人
hyperuricemia
prevalence rate
old people
