摘要
中药挥发油因其对G^+菌、G^-菌、厌氧菌、真菌均有较强的抑制作用而被广泛应用于医疗、食品、农业等多个领域,但是由于其稳定性较差,临床应用并不广泛。环糊精包合技术能够有效提高中药挥发油的稳定性,利于制剂生产的同时还可以提高中药挥发油的生物利用度。笔者参考近年来的文献资料,对抑菌作用不同的中药挥发油以及环糊精包合挥发油的相关研究进行综述,以期为深入研究中药挥发油的抑菌作用、优化中药挥发油环糊精包合技术以及开发更多抑菌挥发油制剂提供参考。
The volatile oil from traditional Chinese medicine has been widely used in medicine, food, agriculture and many other fields as its significant antibacterial effect on gram positive bacteria, gram negative bacteria, anaerobic bacteria and fungus.The clinical application is still not popular due to the poor stability.Cyclodextrin is used as the inclusion material to enhance the stability of volatile oil, make the preparation of production more convenient and the bioavailability improved.The literature referred to antibacterial volatile oil and the inclusion technology were summerized in order to provide reference to intensive study, optimize the technology of inclusion and develop more preparations.
出处
《药学实践杂志》
CAS
2017年第5期394-397,共4页
Journal of Pharmaceutical Practice
基金
江苏大学医学临床科技发展基金项目资助(JLY2014072)
六院联合体课题资助
关键词
中药挥发油
抑菌
环糊精
volatile oil
anti-bacteria
cyclodextrin
