摘要
血清胆碱酯酶(ChE)由肝实质细胞合成,合成后立即释放入血,故测定血清ChE可作为肝功能的一项客观敏感指标。血清ChE作为肝功能状态评价的独立因素应用于临床的时间较长,其不仅能够敏感地反映肝脏的合成功能,而且有助于判断肝病的严重程度。血清ChE与血清前白蛋白、总胆固醇、总胆汁酸、凝血酶原时间等联合检测对于肝病诊疗具有重要价值。同时,血清ChE联合CTP分级或终末期肝病模型评分可更准确地评估肝脏的储备功能,有助于肝病患者的预后判断。
Serum cholinesterase（ ChE） is synthesized by hepatic parenchymal cells and is released into blood immediately after synthesis,and therefore,serum ChE can be used as an objective and sensitive indicator of liver function. Serum ChE has been used as an independent factor for the evaluation of liver function for a long time and can reflect the synthetic function of the liver and help to determine the severity of liver diseases. Combined measurement of serum ChE and serum prealbumin,total cholesterol,total bile acid,and prothrombin time has an important value in the diagnosis and treatment of liver diseases. At the same time,serum ChE combined with Child-Turcotte-Pugh score or MELD score can accurately evaluate liver reserve function,which may help with the prognostic evaluation of patients with liver diseases.
作者
孔剑
向晓星
KONG Jian X(Clinical Medical College of Yangzhou University, Northern Jiangsu People＇s Hospital, Yangzhou, Jiangsu 225001, China)
出处
《临床肝胆病杂志》
CAS
2017年第9期1806-1809,共4页
Journal of Clinical Hepatology
关键词
胆碱酯酶类
肝疾病
诊断
治疗
综述
cholinesterases
liver disease
diagnosis
therapy
review
