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血小板生成素受体激动剂改善重型再生障碍性贫血疗效的研究进展 被引量:4

Advances on thrombopoietin receptor agonist in severeaplastic anemia
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摘要 采用抗胸腺/淋巴细胞球蛋白(ATG/ALG)联合环孢素A的免疫抑制疗法(IST)可使约70%的重型/极重型再生障碍性贫血(再障)患者获得血液学反应…,未能获得血液学反应或反应质量欠佳者,可能与其治疗前残存造血干/祖细胞数量过少和(或)质量缺陷有关。研究表明再障患者残存造血细胞越多IST疗效越好,扩增体内残存造血干细胞的策略可能有助于提高再障IST的血液学反应率。
作者 杜俊 张凤奎
出处 《中华血液学杂志》 CAS CSCD 北大核心 2017年第9期813-816,共4页 Chinese Journal of Hematology
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