摘要
目的 探讨磁共振成像检查（MRI）发现骨性关节炎（OA）患者骨髓病变（BML）的发生情况，分析BML发生的相关危险因素。 方法 140例OA患者均行MRI检查，分析BML发生率。按照检查结果分为BML组和非BML组，问卷收集可能的危险因素，并进行单因素和多因素分析。 结果 本研究140例患者，共78例发生BML，BML发生率为55.71%。单因素分析结果表明：年龄、体质量指数（BMI）、病程、抽烟、饮酒等因素是OA患者并发BML的危险因素（χ2＝5.712、6.661、8.762、4.294、5.565，P〈0.05）。多因素分析结果显示：病程≥3年、BMI≥25kg/m2、年龄≥60岁、饮酒≥3次/周、抽烟每天≥10支是OA患者发生BML的主要危险因素（OR＝3.187、1.984、1.429、1.328、1.082，P〈0.05）。 结论 OA患者发生BML的风险较高。OA患者BML发生与年龄、BMI、病程、饮酒、抽烟等具有一定的关系。
Objective To investigate the incidence of bone marrow lesion （BML） in patients with osteoarthritis （OA） by MRI and analyze the risk factors of BML. Methods A total of 140 OA pa- tients were taken as the objects and were examined by MRI to inivestigate the incidence of BML. All pa- tients were divided into BML group and non BML group according to the examination results. The possi- ble risk factors were collected by questionnaire and analyzed by the single factor and multi-factor analy- sis. Results Among the 140 cases, 78 cases suffered BML, and the incidence of BML was 55.71%. Single factor analysis showed that age, body mass index （BMI）, duration, smoking, drinking were the risk factors on complication of BML in patients with OA （ χ2 = 5.12, 6. 661, 8. 762, 4. 294, 5. 565, P 〈 0. 05 ）. Multi-factor analysis showed that duration≥ 3 years, BMI≥25 kg/m2, age ≥60, drinking≥ 3 times a week, smoking≥10 every day were the major risk factors for the incidence of BML in patients with OA （ OR = 3. 187, 1. 984, 1. 429, 1. 328, 1. 082, P 〈 0. 05 ）. Conclusions OA patients have higher risk of BML. BML in patients with OA is correlated with age, BMI, duration, smoking and drinking.
出处
《中国实用医刊》
2017年第17期105-108,共4页
Chinese Journal of Practical Medicine
关键词
骨性关节炎
磁共振成像检查
骨髓病变
危险因素
Osteoarthritis
Mangetic resonance imaging
Bone marrow lesion
Risk factor
