摘要
目的初步探讨含左氧氟沙星、埃索美拉唑的三联方案抗幽门螺杆菌(Hp)的效果。方法选取2015年8月—2016年8月期间在该院门诊接受诊治的Hp感染患者67例,其中采用左氧氟沙星、埃索美拉唑、阿莫西林三联方案治疗者34例归为观察组,另33例患者采用埃索美拉唑、克拉霉素、阿莫西林三联方案治疗归为对照组,观察比较两组患者的Hp根除率和不良反应发生情况。结果观察组Hp根除率(91.2%)略高于对照组(87.9%),组间差异无统计学意义(P>0.05)。观察组与对照组不良反应发生率分别为11.8%、15.2%,组间差异无统计学意义(P>0.05)。结论含左氧氟沙星、埃索美拉唑的三联方案抗Hp效果显著,可有效根除Hp,且不良反应少,安全性较高,值得推广应用。
Objective This paper tries to evaluate the efficacy of a triple regimen containing levofloxacin and e s -omeprazole in the treatment of helicobacter pylori. Methods 67 patients with Hp infection in this hospital from August 2015 to August 2016 were selected, among which, 34 cases adopted esomeprazole, levofloxacin and amoxicillin triple therapy were classified as the observation group, another 33 cases were treated with esomeprazole, clarithromycin and amoxicillin triple therapy were classified as the control group, Hp eradicat ion rate and the incidence of adverse reac-tions were compared between the two groups. Results The eradication rate of Hp in the observation group was 9 1.2%, slightly higher than that in the control group of 87.9%, but there was no significant difference between the two groups （P〉0.05）. The incidence of adverse reactions in the observation group and the control group were 11.8% and 15.2% re-spectively. There was no significant difference between the two groups （P〉0.05）. Conclusion The triple regimen con-taining levofloxacin and esomeprazole has obvious anti-Hp effect, which can effectively eradicate Hp, and reduce the adverse reactions, with higher safety. It is worth popularization.
出处
《系统医学》
2017年第13期65-67,共3页
Systems Medicine
