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肺功能与FeNO在儿童支气管哮喘规范化治疗过程中的变化及意义 被引量:8

Changes and significance of pulmonary function and FeNO in the standard management of bronchial asthma in children
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摘要 目的分析肺功能与FeNO在儿童支气管哮喘规范化治疗过程中的变化及意义。方法选取2016年5月至2017年4月我科室收治的130例支气管哮喘患儿作为研究对象,按随机数表法,随机分为观察组与对照组,每组65例。对照患儿给予常规支气管哮喘治疗,观察组患儿在此基础上给予支气管哮喘规范化治疗,主要包括了建立相关档案,进行相关教育知识宣传,观察并比较两组患儿的FeNO与肺功能的变化、治疗效果以及患者的治疗满意度。结果治疗后,观察组患儿的FCV、FEV_1、FEV_1/FCV值显著高于对照组患者的FCV、FEV_1、FEV_1/FCV值,观察组患儿的FeNO值显著低于对照组患儿的FeNO值,差异具有统计学意义(P<0.05);治疗后,观察组患儿的治疗总有效率(98.46%)显著高于对照组患儿治疗总有效率(84.62%),差异具有统计学意义(P<0.05),治疗后,观察组患儿的治疗总满意度(96.92%)显著高于对照组患儿治疗总有效率(80.00%),差异具有统计学意义(P<0.05);结论在哮喘儿童规范化的治疗过程中,患儿肺功能值逐渐增加,FeNO的水平值逐渐下降,其具有这广泛临床价值,值得推广与应用。 Objective To analyze the changes and significance of pulmonary function and FeNO in the standardization of bronchial asthma in children. Methods From January 2016 to April 2017, 130 children with bronchial asthma were enrolled in our department. The random number table was randomly divided into observation group and control group (n = 65). In the control group, the patients were treated with conventional bronchial asthma. The children in the observation group were given standardized treatment of bronchial asthma, including the establishment of related files, the relevant educational knowledge publicity, observed and compared the two groups of children with FeNO and pulmonary function changes, The therapeutic effect, and the patient & apos; s treatment satisfaction, Results After treatment, the FCV, FEV1, FEV1 / FCV values of the observation group were significantly higher than those of the control group, the FEV1 and FEV1 / FCV values of the observation group were significantly lower than those of the control group (98.46%) was significantly higher than that in the control group (84.62%), and the difference was statistically significant (P 〈0.05). After treatment, the total effective rate (98.46%) in the observation group was significantly higher than that in the control group (P 〈0.05). After treatment, the total satisfaction (96.92%) in the treatment group was significantly higher than that in the control group (80.00%), the difference was statistically significant (P 〈0.05). Conclusion In the course of standard- ized treatment of children with asthma, the pulmonary function value of children gradually increased, the level of FeNO decreased gradually, which has this wide clinical value, worthy of promotion and application.
作者 张金山 曹玲
出处 《北京医学》 CAS 2017年第8期830-833,共4页 Beijing Medical Journal
关键词 肺功能 FENO 儿童 支气管哮喘 pulmonaryfunction FeNO children bronchialasthma
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