摘要
目的探讨复方玄驹胶囊配合枸橼酸氯米芬及相关基础治疗对多囊卵巢综合征(PCOS)患者排卵及助孕的效果。方法 76例PCOS所致不孕患者,按照患者就诊先后将其分为联合组与单纯组,各38例。所有患者均给予基础治疗,单纯组患者在月经第3~5天给予枸橼酸氯米芬胶囊治疗,联合组患者在单纯组治疗基础上给予复方玄驹胶囊,治疗结束后评价两组患者排卵情况,并对出现排卵患者进行随访,观察患者临床妊娠率。结果治疗后联合组子宫内膜生长情况明显优于单纯组,成熟卵泡多于单纯组,差异有统计学意义(P<0.05)。两组患者治疗前促卵泡激素(FSH)、促黄体生成素(LH)、睾酮(T)水平比较差异无统计学意义(P>0.05);治疗后联合组患者FSH、LH、T水平明显优于单纯组,差异有统计学意义(P<0.01)。单纯组患者治疗后排卵例数为24例,联合组为33例,比较差异有统计学意义(P<0.05),单纯组患者治疗后妊娠例数为20例,联合组患者妊娠例数为29例,比较差异有统计学意义(P<0.05)。结论复方玄驹胶囊配合枸橼酸氯米芬胶囊治疗PCOS能够有效提高患者卵泡发育,促进排卵率,提高患者妊娠可能,临床效果满意,值得应用推广。
Objective To investigate the ovulation and progesterone effect of compound Xuanju capsule combined with c[omiphene citrate and related basic treatment for polycystic ovary syndrome （PCOS） patients. Methods A total of 76 PCOS caused infertility patients were divided by visiting order into combined group and single group, with 38 cases in each group. All patients received basic treatment, and the single group was treated with clomiphene citrate in menstruation 3-5 d. The combined group received compound Xuanju capsule on the basis of the combined group. After treatment, ovulation condition was evaluated in two groups, and patients with ovulation were followed-up, to observe their clinical pregnancy rate. Results After treatment, the combined group had better endometrial growth than the single group, and more mature follicle than the single group. Their difference had statistical significance （P〈0.05）. Both groups had no statistically significant difference in follicle stimulating hormone （FSH）, luteinizing hormone （LH） and testosterone （T） levels before treatment （P〉O.05）. After treatment, the combined group had obviously better FSH, LH and T level than the single group, and their difference had statistical significance （P〈O.O1）. After treatment, the single group had ovulation number as 24 cases, which was 33 cases in the combined group, and their difference had statistical significance （P〈O.05）. After treatment, the sing-,e group had pregnancy number as 20 cases, which was 29 cases in the combined group, and their difference had statistical significance （P〈0.05）. Conclusion Combination of compound Xuanju capsule and clomiphene citrate capsules shows satisfactory clinical effect in treating PCOS, and it can effectively improve follicular development, promote ovulation rate, an improve the possibility of pregnancy. So it is worthy of apphcation and promotion.
出处
《中国实用医药》
2017年第21期16-18,共3页
China Practical Medicine
关键词
多囊卵巢综合征
复方玄驹胶囊
促排卵治疗
助孕效果
Polycystic ovary syndrome
Compound Xuanju capsule
Ovulation induction therapy
Progesterone effect
