摘要
目的 分析脂肪乳氨基酸(17)葡萄糖(11%)注射液(卡文注射液)对食管癌术后患者营养支持的临床效果。方法 选取本院胸外科2014年12月-2016年12月收治的68名食管癌患者,随机分为2组,各34例。均行食管癌手术治疗,研究组术后输注卡文注射液,对照组术后行常规补液治疗。应用主观全面评定法(SGA)对患者进行营养评定,记录并比较2组患者体质量、血清总蛋白(TSP)、血清白蛋白(Alb)、转铁蛋白(TF)含量、1周内尿素氮含量、营养不良改善情况以及并发症发生情况。结果 2组患者食管癌术后体重均有下降,研究组患者体重下降明显低于对照组,差异有统计学意义(P〈0.01);研究组患者TSP、Alb、TF下降程度明显低于对照组,差异有统计学意义(P〈0.05);2组患者负氮平衡均有所改善,研究组患者负氮平衡改善情况优于对照组,差异有统计学意义(P〈0.01);2组患者食管癌术后营养不良均有所改善,研究组患者营养不良改善程度优于对照组,差异有统计学意义(P〈0.05);研究组并发症发生率低于对照组并发症发生率,差异有统计学意义(P〈0.05)。结论 与传统术后补液方法相比,卡文注射液提高食管癌术后患者机体机能的恢复效果,改善患者的负氮平衡和营养不良状况,降低并发症发生率,改善临床预后。
Objective To analyze the clinical effect of nutritional support for postoperative patients with esophageal cancer with fat emulsion and amino acids (17) and glucose (11%) injection (Calvin injection). Methods A total of 68 patients with esophageal cancer treated in the chest surgery in our hospital from December 2014 to December 2016 were selected and randomly divided into two groups with 34 cases in each group. All patients were treated with surgery for esophageal cancer. The patients in the study group were treated with Calvin injection after operation while patients in the control group were treated with conventional fluid replacement therapy. Subjective comprehensive assessment (SGA) was used to assess the nutritional status of the patients and the weight, serum total protein (TSP), serum albumin (Alb), transferrin (TF) content, urea nitrogen content in on one week, malnutrition improvement and complications of the patients in two groups were recorded and compared. Results The weight of the patients with esophageal cancer in the two groups after operation was decreased, and the weight loss of the patients in the study group was lower than that of the control group and the difference was statistically significant (P〈0.01). The decrease degree of TSP, Alb and TF in the study group was lower than that in the control group, and the difference was statistically significant (P〈0.05). The negative nitrogen balance of the two groups was improved, and the improvement of the negative nitrogen balance in the study group was better than that in the control group, and the difference was statistically significant (P〈0.01). The postoperative malnutrition in the patients with esophageal cancer was improved. The improvement degree of malnutrition in the study group was better than that in the control group, and the difference was statistically significant (P〈0.05). The incidence of complications in the study group was lower than that in the control group, and the difference
出处
《中国生化药物杂志》
CAS
2017年第8期24-26,共3页
Chinese Journal of Biochemical Pharmaceutics