摘要
目的探讨分析依达拉奉治疗急性有机磷中毒合并呼吸衰竭的临床疗效。方法回顾性分析54例急性有机磷中毒合并呼吸衰竭患者的临床记录资料,将其随机分为两组。治疗组27例,应用依达拉奉治疗;对照组27例,应用常规治疗。治疗后,比较两组疗效。结果治疗组的有效率大于对照组,治疗24 h、治疗48 h、治疗72 h的血清胆碱酯酶活力均高于对照组,治疗后的PaO_2、SaO_2均高于对照组,自主呼吸恢复时间、意识恢复时间、呼吸机使用时间、住院时间均少于对照组,差异均具有统计学意义(P<0.05)。结论依达拉奉治疗急性有机磷中毒合并呼吸衰竭的临床疗效显著,值得临床推广。
Objective To explore the clinical efficacy of edaravone in the treatment of acute organophosphate poisoning complicated with respi- ratory failure. Methods The clinical data of 54 patients with acute organophosphate poisoning and respiratory failure who were treated that retro- spectively analyzed. They were randomly divided into two groups. Treatment group of 27 cases, the application of edaravone treatment; control group of 27 cases, the application of conventional treatment. After treatment, the two groups were compared. Results The effective rate of the treat- ment group was higher than that of the control group, treatment 24 h, treatment 48 h, 72 h treatment of serum cholinesterase activity were higher than the control group, after treatment PaO2, SaO2 were higher than the control group, spontaneous breathing recovery time, consciousness （P〈0.05）, and the time of ventilator was shorter than that of the control group. The difference was statistically significant （P〈0.05）. Conclusion The clinical effi- cacy of edaravone in the treatment of acute organophosphate poisoning complicated with respiratory failure is remarkable and deserves clinical pro- motion.
出处
《当代医学》
2017年第22期50-52,共3页
Contemporary Medicine
关键词
依达拉奉
磷中毒
呼吸衰竭
急性
效果
Edaravone
Phosphorus poisoning
Respiratory failure
Acute
