摘要
随着溴系阻燃剂（BFR）在全球范围内的限制使用,有机磷阻燃剂（OPFRs）作为其优秀替代品,需求量和使用量正快速增长.然而,OPFRs也会在生产和使用过程中向周围环境释放,且具有一定的环境持留性.部分OPFRs被证实具有神经、生殖、致癌等毒性.目前,OPFRs已在各种环境介质中广泛存在,并可能通过各种途径进入人体,对人体健康造成潜在危害.本文综述了OPFRs在空气、灰尘、饮用水、膳食等与人体暴露途径相关的环境介质中的残留水平和组成特征,及其人体暴露研究进展,并对该研究内容未来的研究方向进行了展望.
Organophosphate flame retardants （OPFRs）, which have both great properties of flame retardation and plasticization, are currently widely used as additive flame retardants. Due to the restriction and phase-out of brominated flame retardants （BFRs）, the market demand for OPFRs as excellent alternatives of BFRs has been rapid increasing. OPFRs can be slowly released into the environment during production and application. Some OPFRs might be persistent in the environment. As a result, OPFRs have been detected in various matrices in the environment and are expected to accumulate in human body through various pathways. OPFRs may cause adverse effects to human health as some of them have been identified as neurotoxicants, reproductive toxicants and potential carcinogens. The article summarized the occurrence and patterns of OPFRs in various environmental matrices such as air, dust, water, food and so on, and in human specimens, estimates the exposure status through different pathways and body burdens of OPFRs. The expected hotspots of OPFRs were also discussed in the future.
作者
丁锦建
杨方星
Ding Jinjian Yang Fangxing(Key Laboratory of Environment Remediation and Ecological Health, Ministry of Education, College of Environmental and Resource Sciences, Zhejiang University, Hangzhou 310058,China)
出处
《中华预防医学杂志》
CAS
CSCD
北大核心
2017年第6期570-576,共7页
Chinese Journal of Preventive Medicine
基金
国家自然科学基金（21377108）
浙江大学空气污染与健康研究中心项目（H20151885）
关键词
环境暴露
有机磷化合物
阻燃剂
Environmental exposure
Organophosphorus compounds
Flame retardants
