摘要
目的比较胺碘酮和普罗帕酮治疗心律失常的临床疗效及对血清高敏C反应蛋白水平(hypersensitive C-reactive protein,hs-CRP)的影响。方法将我院2015年12月~2016年12月收治的96例心律失常患者随机分为胺碘酮组和普罗帕酮组,各48例。普罗帕酮组予盐酸普罗帕酮片口服治疗,胺碘酮组予盐酸胺碘酮片口服治疗,比较两组患者治疗的总有效率、血清hs-CRP水平变化。结果治疗后,胺碘酮组总有效率(95.83%)高于普罗帕酮组总有效率(83.33%),差异有统计学意义(P<0.05);治疗后,两组患者血清hs-CRP水平均明显降低,胺碘酮组患者血清hs-CRP[(7.63±2.60)mg/L]低于普罗帕酮组[(12.56±3.50)mg/L],差异有统计学意义(P<0.05)。结论心律失常患者采用胺碘酮治疗,疗效较普罗帕酮更好,且其降低血清hs-CRP水平的能力更强,值得临床推广使用。
Objective To compare the clinical effect of Propafenone and Amiodarone in treatment of arrhythmia and their influence on serum hypersensitive C-reactive protein （hs-CRP）.nethods 96 patients with arrhythmia treated in our hospital from Decembere 2015 to December 2016 were randomly divided into Propafenone group and Amiodarone group,with 48 cases in each group.Patients in the Propafenone group were orally given Propafenone hydrochloride tablets,and those in the Amiodarone group were orally given Amiodarone hydrochloride tablets.The overall response rates and changes of serum hs-CRP level were compared.Results After treatment,the overall response rate in the Amio- darone group was 95.83%,significantly higher than the 83.33% in the Propafenone group （P〈0.05）.After treatment,the levels of serum hs-CRP were evidently lowered in both groups,and the hs-CRP level was significantly lower in the Amiodarone group [（7.63±2.60） mg/L] than that in the Propafenone group[（12.56±3.50） mg/L].Conclusion The effect of Amiodarone is better than that of Propafenone in treatment of arrhythmia, and Amiodarone is more effective in lowering the level 0f serum hs-CRP, thus is worthy to he promoted.
作者
金伟
JIN Wei(Department of the Second Cardiology,the Third Hospital of Nanchang in Jiangxi Province,Nanchang 330009,Chin)
出处
《中国当代医药》
2017年第15期40-42,共3页
China Modern Medicine
关键词
普罗帕酮
胺碘酮
心律失常
高敏C反应蛋白
Propafenone
Amiodarone
Arrhythmia
Hypersensitive C-reactive protein
