摘要
目的研究稳心颗粒对冠心病快速心律失常病人的临床疗效和对甲襞微循环的影响。方法90例冠心病心律失常病人,随机分为两组,治疗组予稳心颗粒3粒,每日3次;对照组予胺碘酮0.2g,每日3次,1周后改为0.2g,每日2次,再1周后改为0.2g,每日1次,疗程皆为4周。治疗前后分别对临床症状、Holter心律失常进行等级评定,并检查三大常规、肝肾功能、心电图、胸片及甲襞微循环。结果冠心病心律失常病人的相关临床症状缓解总有效率治疗组为95.7%,优于对照组的83.7%(P<0.01),Holter心律失常的总有效率治疗组为68.9%,与对照组的76.6%比较差异无统计学意义(P>0.05),改善甲襞微循环治疗组优于对照组(P<0.01或P<0.05)。治疗组未见副反应。结论稳心颗粒对冠心病快速心律失常的控制率与胺碘酮相当,改善相关临床症状及甲襞微循环方面优于胺碘酮;且毒副反应少,安全性高于胺碘酮。
Objective To observe the effect of Wenxin Granules on clinical efficacy and nail fold microcirculation in coronary heart disease with tachycardiac arrhythmia. Methods Ninety patients with coronary heart disease and tachycardiac arrhythmia were randomly divided into treatment group （n = 47） treated with Wenxin Granules and control group （n = 43） treated with amiodarone, The symptoms, laboratory assay of blcxxt and urine, Monitor Holter, nail fold microcirculation, the function of liver, kidney and thyroid gland and chest - X - ray were analyzed pre- and post - treatment, Results The total effective rate for tachycardiac arrhythmia and symptoms related to arrhythmia were 68, 9% and 95, 7% in treatment group, Those were 76,696 and 83,796 in control group （P〉0, 05）, The nail fold microcirculation was improved significantly （P 〈 0, 01 ） in treatment group but it was not in control group （P 〉0.05） after treatment, Conclusion Wenxin Granules had similar efficacy to the arniodarone for tachycardiac arrhythmia in coronary heart disease and the effect of improving symptoms related to arrhythmia and nail fold microcirculation was superior to amiodarone, There were no adverse reactions, It was safe.
出处
《中西医结合心脑血管病杂志》
2007年第6期474-476,共3页
Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
关键词
稳心颗粒
冠心病
心律失常
甲襞微循环
胺碘酮
Wenxin Granules
coronary heart disease
arrhythmia
nail fold rnicrocirculation
arniodarone
