摘要
目的对奥沙利铂与卡培他滨联合化疗应用于进展期胃癌治疗中的临床效果进行研究。方法选取82例2013年5月—2016年12月在我院接受治疗的进展期胃癌患者作为研究对象,并1∶1随机分为对照组(接受替吉奥联合奥沙利铂治疗)和实验组(接受奥沙利铂联合卡培他滨治疗),每组各41例,对两种治疗方法的效果进行对照研究。结果就治疗总有效率而言,实验组患者高于对照组(90.24%vs.70.73%);就不良反应发生情况而言,实验组患者的发生率低于对照组,发生程度轻于对照组,组间对比,差异具有统计学意义(P<0.05)。结论奥沙利铂与卡培他滨联合化疗应用于进展期胃癌治疗中的临床效果理想。
Objective To study the clinical effect of oxaliplatin combined with capecitabine in the treatment of advanced gastric cancer. Methods 82 cases of patients with advanced gastric cancer from May 2013 to December 2016 in our hospital were randomly divided into control group （treated with tegafur combined with oxaliplatin） and experimental group （treated with oxaliplatin combined with capecitabin） by random 1：1 method, 41 patients in each group, the treatment effect were compared. Results The total efficiency of treatment of patients in the experimental group was significantly higher than that of the control group （90.24% vs.70.73%）; on the occurrence of adverse reactions, patients in the experimental group was significantly lower than the control group, the occurrence degree was lighter than the control group, P〈0.05, the difference was statistically significant. Conclusion The clinical efficacy of oxaliplatin combined with capecitabine in the treatment of advanced gastric cancer is very satisfactory.
出处
《中国继续医学教育》
2017年第11期180-181,共2页
China Continuing Medical Education
关键词
奥沙利铂
卡培他滨
进展期胃癌
oxaliplatin
capecitabine
advanced gastric cancer
