摘要
目的分析无菌体液(血液、胸腹水、胆汁等)的细菌培养结果,了解病原菌的分布和对抗菌药物的耐药性,为临床合理运用抗生素提供参考依据。方法对本院2012年1月-2015年12月1 520份无菌体液标本进行细菌培养鉴定和药敏试验,并用WHONET对结果进行统计分析。结果 1 520份标本中共分离出500株细菌,阳性率为32.9%,其中革兰阳性菌146株,占29.2%,以金黄色葡萄球菌为主(85/146);革兰阴性菌331株,占66.2%,以大肠埃希菌为主(128/331);真菌23株,占4.6%,以白色念珠菌为主(21/23)。未发现对万古霉素、替考拉宁和利奈唑胺耐药的金黄色葡萄球菌。结论无菌体液中最常见的病原菌是大肠埃希菌、金黄色葡萄球菌和奇异变形杆菌。了解病原菌的分布特点和耐药模式有利于临床合理使用抗生素。
Objective To analyze the bacterial cuhure results of sterile body fluids （blood, chest water, bile, etc. ）, to under- stand the distribution of pathogens and antimicrobial drug resistance, and to provide reference for clinical rational use of antibiot- ics. Methods From January 2012 to December 2015, 1 520 aseptic humoral specimens in our hospital were used to identify the bacterial culture and drug susceptibility test and the results were statistically analyzed by WHONET. Results 500 strains of bacteria were separated out from a total of 1 520 specimens with a positive rate of 32.9%. Gram - positive bacteria were 146 strains accounting for 29.2%, the main of which were Staphylococcus aureus （ 85/146 ）. Gram - negative bacteria were 331 strains accounting for 66.2% , the main of which were Escherichia coli（ 128/331 ）. Fungi were 23 strains accounting for 4.6% , the main of which were Candida albicans（ 21/23 ）. Drug resistance of Staphylococcus aureus to vancomycin, stead ning and rina thiazole amine were not found. Conclusion The most common pathogenic bacteria in sterile body fluids are Escherichia coli, Staphylococcus aureus and Singular proteus. Better understanding of the pathogenic bacteria distribution and drug resistance pat- terns is helpful for clinical rational use of antibiotics.
出处
《中国卫生检验杂志》
CAS
2017年第8期1187-1189,共3页
Chinese Journal of Health Laboratory Technology
关键词
耐药性监测
无菌体液
细菌分布
Drug resistance surveillance
Sterile body fluids
Bacterial distribution
