摘要
目的研究初诊2型糖尿病合并非酒精性脂肪肝脂肪含量的相关因素。方法选取2014年6月~2015年6月我院90例初诊2型糖尿病患者为研究对象,合并组患者为45例2型糖尿病合并非酒精性脂肪肝患者,对照组患者为45例2型糖尿病且无其他病症,分别测定BMI、WHR、FBG、HDL-C、LDL-C、GH、FINS、TC、TG指标水平。结果两组患者在肥胖、超重、高血压、高TC及高TG指标方面,合并组的每项患病率均高于对照组,尤其在超重及高TG两项更加显著,差异有统计学意义(χ~2=9.5255,P=0.0020;χ~2=9.6797,P=0.0019);合并组患者的BMI、WHR、FBG、HDL-C、LDL-C、GH、FINS每项指标均明显高于对照组,尤其在BMI、HDL-C、LDL-C及GH水平分别为(27.4±3.4)kg/m2、(1.25±0.34)mmol/L、(2.72±0.21)mmol/L、(12.50±1.41)%,差异有统计学意义(t=8.9195,P=0.0000;t=2.0411,P=0.0442;t=7.1857,P=0.0000;t=12.6289,P=0.0000);合并组患者TC、TG指标水平分别为(6.25±1.62)mmol/L、(3.35±0.91)mmol/L,均显著高于对照组,尤其是TG更加明显,差异有统计学意义(t=2.5284,P=0.0132;t=3.1841,P=0.0020)。结论初诊2型糖尿病合并非酒精性脂肪肝患者的脂肪含量与BMI、GH、TC、TG等因素相关,可提供有效的早诊断早发现标准,减缓患者病情恶化。
Objective To study the relevant factors of fat content in newly diagnosed type 2 diabetes mellitus complicated with nonalcoholic fatty liver. Methods 90 patients with newly diagnosed type 2 diabetes mellitus who were diagnosed in our hospital from June 2014 to June 2015 were selected as the study subjects. 45 patients in the combined group were with type 2 diabetes complicated with nonalcoholic fatty liver. 45 patients in the control group were with type 2 diabetes without complications. The levels of BMI, WHR, FBG, HDL-C, LDL-C, GH, FINS, TC and TG were measured respectively. Results From the indices of obesity, overweight, hypertension, high TC and high TG indices in the two groups, the prevalence rate of each index in the combined group was significantly higher than that in the control group, especially in overweight and high TG. There were significant differences between the two groups （X^2=9.5255, P=0.0020; X^2=9.6797, P=0.0019）; the levels of BMI, WHR, FBG, HDL-C, LI）L-C, GH and FINS in the combined group were significantly higher than those in the control group, especially in the levels of BMI, HI）L-C, LDL-C and GH[（27.4±3.4） kg/m2, （1.25±0.34） retool/L, （2.72±0.21） retool/L, （12.50±1.41）%], and the difference was more significant and was statistically significant（t=8.9195, P=0.0000; t=2.0411, P=0.0442; t=7.1857, P=0.0000; t= 12.6289, P=0.0000）; the levels of TC and TG in the combined group were（6.25±1.62） mmol/L and （3.35±0.91） mmol/L respectively, which were significantly higher than those in the control group, especially for TG. The differences were statistically significant （t=2.5284, P=0.0132; t=3.1841, P=0.0020）. Conclusion The fat content in the patients with newly diagnosed type 2 diabetes mellitus complicated with nonalcoholic fatty liver are closely related to BMI, GH, TC and TG. This can provide an effective early diagnosis and early detection criteria, so as to slow the deterioration of patient＇s conditions.
出处
《中国现代医生》
2017年第9期20-22,27,共4页
China Modern Doctor
基金
浙江省温州市科技计划项目(Y20140285)
