摘要
目的探讨2型糖尿病(T2DM)患者非酒精性脂肪肝(NAFLD)的患病率及相关危险因素。方法 T2DM患者98例,根据B超检查结果分为有NAFLD组(A组,50例)和无NAFLD组(B组,48例),检测两组糖化血红蛋白(HbA1c)、空腹血糖(FBG)、餐后2-h血糖(PBG)和血脂,计算体重指数(BMI)。结果 A组BMI、HbA1c、FBG、PBG和甘油三酯均高于B组(P<0.05),高密度脂蛋白胆固醇(HDL-C)低于B组(P<0.01)。喜肉食、BMI、PBG为影响NAFLD的危险因素。结论合并NAFLD的T2DM患者糖、脂代谢更紊乱。
Objective To investigate the incidence of nonalcoholic fatty liver disease(NAFLD)in 98 patients with type 2diabetes mellitus(T2DM)and analyze the risk factors for NAFLD.Methods Body mass index(BMI),glycated hemoglobin 1c(HbA1c),fasting blood glucose(FBG)were examined in 50T2 DM patients with NAFLD(group A)and 48 T2 DM patients without NAFLD(group B),which were diagnosed by quantitative ultrasound liver fat examination.Results BMI,HbA1 c,FBG,PBG and triglyceride were significantly higher,but high density lipoprotein cholesterol was significantly lower,in group A than those in group B(P〈0.05,P〈0.01).The BMI,PBG and meat crushers were the risk factors for NAFLD.Conclusion T2 DM patients with NAFLD have worse glucose and lipid metabolism.
出处
《江苏医药》
CAS
北大核心
2014年第21期2548-2550,共3页
Jiangsu Medical Journal
基金
南京市医药科技发展项目(YKK11092)
南京市科技发展项目(2013ZD005)
关键词
2型糖尿病
非酒精性脂肪肝
Type 2diabetes mellitus
Nonalcoholic fatty liver disease