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行为治疗——非酒精性脂肪性肝病的基础治疗

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摘要 非酒精性脂肪性肝病(nonalcoholic fatty liver disease,NAFLD)是指除外酒精和其他明确的肝损害因素所致的,以弥漫性肝细胞大泡性脂肪变为主要特征的临床病理综合征.NAFLD可以进展为非酒精性脂肪性肝炎(nonalcoholic steatohepatitis,NASH),进而导致肝硬化和肝细胞癌.在西方国家,NAFLD是最常见的慢性代谢性肝病,患病率为25%~30%[1],现已被认为是导致肝酶升高的最常见原因[2-3].近年来,我国由于肥胖、2型糖尿病和代谢性疾病患病率的升高,NAFLD患者越来越多,人们生活方式的改变也是导致NAFLD患者增多的重要原因.由于NAFLD和代谢综合征密切相关[4],并且肝脂肪含量的增加是心血管疾病、胰岛素抵抗和2型糖尿病的独立危险因素[5],所以NAFLD的治疗受益并不仅限于肝脏本身.现阶段,NAFLD药物治疗的应用由于诸多原因而受限,同时鉴于NAFLD与肥胖和心血管疾病的关系,饮食和运动干预,即行为治疗的两个主要方面,越来越受到重视.
出处 《中华临床医师杂志(电子版)》 CAS 2012年第20期17-19,共3页 Chinese Journal of Clinicians(Electronic Edition)
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参考文献5

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二级参考文献45

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