摘要
活血化瘀类中药(单味药、复方)可通过降低血脂,抑制炎症反应,改善内皮功能,抑制血管壁的微血管新生,减少基质金属蛋白酶表达,抑制斑块增殖和破溃,稳定易损斑块,改善患者临床症状积分等多途径和多靶点干预颈动脉粥样硬化的发生与发展,减少心脑血管事件的发生。
Traditional Chinese medicine for activating blood circulation and removing blood stasis (single drug and com- pound prescription) has multiple ways and targets for the intervention of occurrence and development of carotid athero- sclerosis, such as reducing blood lipid, inhibiting inflammation and angiogenesis, improving endothelial function, re- ducing the expression of matrix metalloproteinase, restraining the plaque proliferation and rupture, maintaining vulnera- ble plaque stability, improving clinical symptom score and so on, in order to reduce the incidence of cardiovascular e- vents.
出处
《中医药学报》
CAS
2017年第2期119-121,共3页
Acta Chinese Medicine and Pharmacology
基金
国家中医药管理局中医药标准化项目(SATCM-2015-BZ[283])
国家中医药管理局重点专科心血管病科建设项目
陕西省科技统筹创新工程计划项目(2013KTCQ03-05)
陕西中医药大学科研基金项目(2015QN26)
陕西省第五批重点专科心脑血管病科建设项目
关键词
活血化瘀
中药
颈动脉粥样硬化
临床研究进展
Promoting blood circulation and removing blood stasis
Traditional Chinese medicine
Carotid atherosclero-sis
Progress of clinical research